Background: Cantharidin has been categorized as highly toxicant in Chinese medicine. But
cantharidin can efficiently treat different types of diseases, such as molluscum contagiosum …

Cancer is a preeminent threat to the human race, causing millions of deaths each year on
the Earth. Traditionally, natural compounds are deemed promising agents for cancer …

The protein chaperone GRP78 is a master regulator of endoplasmic reticulum (ER) functions
and is frequently over-expressed at the surface of cancer cells where it contributes to chemo …

Although pathological characteristics of fumonisin B1 are known to induce hepatic injury
over prolonged periods, the cellular defense mechanisms against the detrimental effects of …

For many years, major differences in morphology, motility, and mechanical characteristics
have been observed between transformed cancer and normal cells. In this review, we …

Cantharidin (CTD), an important active compound derived from the traditional Chinese
medicine Mylabris (also called Banmao), has been used in the treatment of diseases such …

Cantharidin (CTD), a natural compound derived from Mylabris, is widely used in traditional
Oriental medicine for its potent anticancer properties. However, its clinical application is …

As an active constituent of the beetle Mylabris used in traditional Chinese medicine,
cantharidin is a potent and selective inhibitor of protein phosphatase 2A (PP2A) that plays a …

microRNAs are commonly dysregulated in a number of human cancers, for example,
hepatocellular carcinoma (HCC), but the precise mechanism of dysregulation has not been …

Background: The unfolded protein response (UPR) plays a significant role in maintaining
protein hemostasis in tumor cells, which are crucial for tumor growth, invasion, and …