Joint distribution of protein concentration and cell volume coupled by feedback in dilution

I Zabaikina, P Bokes, A Singh - International Conference on Computational …, 2023 - Springer
We consider a protein that negatively regulates the rate with which a cell grows. Since less
growth means less protein dilution, this mechanism forms a positive feedback loop on the …

The effect of microRNA on protein variability and gene expression fidelity

R Fan, A Hilfinger - Biophysical Journal, 2023 - cell.com
Small regulatory RNA molecules such as microRNA modulate gene expression through
inhibiting the translation of messenger RNA (mRNA). Such posttranscriptional regulation …

Translation regulation by RNA stem-loops can reduce gene expression noise

C Çelik, P Bokes, A Singh - BMC bioinformatics, 2024 - Springer
Background Stochastic modelling plays a crucial role in comprehending the dynamics of
intracellular events in various biochemical systems, including gene-expression models. Cell …

Multivariate Markovian models of biological processes

C Çelik - iam.fmph.uniba.sk
Mathematical models of biochemical processes are essential tools to understanding the
dynamics of intercellular events in living organisms. The copy number of species in such a …