Immunoglobulin A nephropathy (IgAN) is defined by the predominant deposition of IgA in the
glomerular mesangium. Light microscopic appearances and clinical features can vary …

IgA nephropathy (IgAN) is an important cause of progressive kidney disease with 25–30% of
patients developing end-stage renal disease within 20 years of diagnosis. There is still no …

Abstract Background. Immunoglobulin A nephropathy (IgAN) is the most common cause of
chronic renal failure among primary glomerulonephritis patients. The best treatment for IgAN …

BACKGROUND: Recent studies have shown that both steroids and angiotensin-converting
enzyme (ACE) inhibitors improve kidney survival and decrease proteinuria in patients with …

The optimal treatment for IgA nephropathy (IgAN) remains unknown. Some patients respond
to corticosteroids, suggesting that more aggressive treatment may provide additional benefit …

The underlying cause of most glomerular diseases remains an enigma. Infectious agents,
autoimmunity, drugs, inherited disorders, and environmental agents have been implicated …

Although IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis
worldwide, our understanding of the pathogenesis of this complex disease remains limited …

Background IgA nephropathy is the most common glomerulonephritis world‐wide. IgA
nephropathy causes end‐stage kidney disease (ESKD) in 15% to 20% of affected patients …

Results Of the 1076 patients, 100 (10.2%) presented with NS; complete remission (CR),
partial remission (PR), and no response (NR) occurred in 48 (48%), 32 (32%), and 20 (20%) …

Results Histologic analysis based on Shigematsu classification revealed a significant
correlation between levels of u-PCX and severity of acute extracapillary abnormalities (r …