Arterial stiffness and cardiovascular risk in hypertension

P Boutouyrie, P Chowienczyk, JD Humphrey… - Circulation …, 2021 - Am Heart Assoc
Arterial stiffness, a leading marker of risk in hypertension, can be measured at material or
structural levels, with the latter combining effects of the geometry and composition of the …

Large-Artery Stiffness in Health and Disease: JACC State-of-the-Art Review

JA Chirinos, P Segers, T Hughes… - Journal of the American …, 2019 - jacc.org
A healthy aorta exerts a powerful cushioning function, which limits arterial pulsatility and
protects the microvasculature from potentially harmful fluctuations in pressure and blood …

[HTML][HTML] Diretrizes brasileiras de hipertensão arterial–2020

WKS Barroso, CIS Rodrigues, LA Bortolotto… - Arquivos brasileiros de …, 2021 - SciELO Brasil
A hipertensão arterial (HA) é uma doença crônica não transmissível (DCNT) definida por
níveis pressóricos, em que os benefícios do tratamento (não medicamentoso e/ou …

Brazilian guidelines of hypertension–2020

WKS Barroso, CIS Rodrigues, LA Bortolotto… - Arquivos brasileiros de …, 2021 - SciELO Brasil
SciELO - Brasil - Diretrizes Brasileiras de Hipertensão Arterial – 2020 Diretrizes Brasileiras de
Hipertensão Arterial – 2020 Acessibilidade / Reportar erro Brasil Lista alfabética de periódicos …

Biological Versus Chronological Aging: JACC Focus Seminar

MR Hamczyk, RM Nevado, A Barettino, V Fuster… - Journal of the American …, 2020 - jacc.org
Aging is the main risk factor for vascular disease and ensuing cardiovascular and
cerebrovascular events, the leading causes of death worldwide. In a progressively aging …

Arterial stiffness preceding diabetes: a longitudinal study

M Zheng, X Zhang, S Chen, Y Song, Q Zhao… - Circulation …, 2020 - Am Heart Assoc
Rationale: Previous studies on the relationship between diabetes and arterial stiffness were
mostly cross-sectional. A few longitudinal studies focused on one single direction. Whether …

Vascular smooth muscle cells and arterial stiffening: relevance in development, aging, and disease

P Lacolley, V Regnault, P Segers… - Physiological …, 2017 - journals.physiology.org
The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Global burden of hypertension and systolic blood pressure of at least 110 to 115 mm Hg, 1990-2015

MH Forouzanfar, P Liu, GA Roth, M Ng, S Biryukov… - Jama, 2017 - jamanetwork.com
Importance Elevated systolic blood (SBP) pressure is a leading global health risk.
Quantifying the levels of SBP is important to guide prevention policies and interventions …

Chronic supplementation with a mitochondrial antioxidant (MitoQ) improves vascular function in healthy older adults

MJ Rossman, JR Santos-Parker, CAC Steward… - …, 2018 - Am Heart Assoc
Excess reactive oxygen species production by mitochondria is a key mechanism of age-
related vascular dysfunction. Our laboratory has shown that supplementation with the …

Brachial-ankle pulse wave velocity and the risk prediction of cardiovascular disease: an individual participant data meta-analysis

T Ohkuma, T Ninomiya, H Tomiyama, K Kario… - …, 2017 - Am Heart Assoc
An individual participant data meta-analysis was conducted in the data of 14 673 Japanese
participants without a history of cardiovascular disease (CVD) to examine the association of …