Mass spectrometry methods for studying structure and dynamics of biological macromolecules

L Konermann, S Vahidi, MA Sowole - Analytical chemistry, 2014 - ACS Publications
All processes that occur within living organisms are intimately linked to biological
macromolecules such as proteins, nucleic acids, or polysaccharides. Phospholipid …

Applications of infrared multiple photon dissociation (IRMPD) to the detection of posttranslational modifications

P Maitre, D Scuderi, D Corinti, B Chiavarino… - Chemical …, 2019 - ACS Publications
Infrared multiple photon dissociation (IRMPD) spectroscopy allows for the derivation of the
vibrational fingerprint of molecular ions under tandem mass spectrometry (MS/MS) …

Noncovalent complexes of cyclodextrin with small organic molecules: applications and insights into host–guest interactions in the gas phase and condensed phase

J Lee, SS Lee, S Lee, HB Oh - Molecules, 2020 - mdpi.com
Cyclodextrins (CDs) have drawn a lot of attention from the scientific communities as a model
system for host–guest chemistry and also due to its variety of applications in the …

Gas-phase infrared spectroscopy of neutral peptides: Insights from the far-IR and THz domain

S Bakels, MP Gaigeot, AM Rijs - Chemical reviews, 2020 - ACS Publications
Gas-phase, double resonance IR spectroscopy has proven to be an excellent approach to
obtain structural information on peptides ranging from single amino acids to large peptides …

Enhanced basicity of push–pull nitrogen bases in the gas phase

ED Raczyńska, JF Gal, PC Maria - Chemical Reviews, 2016 - ACS Publications
Nitrogen bases containing one or more pushing amino-group (s) directly linked to a pulling
cyano, imino, or phosphoimino group, as well as those in which the pushing and pulling …

Perspective: Electrospray photoelectron spectroscopy: From multiply-charged anions to ultracold anions

LS Wang - The Journal of Chemical Physics, 2015 - pubs.aip.org
Electrospray ionization (ESI) has become an essential tool in chemical physics and physical
chemistry for the production of novel molecular ions from solution samples for a variety of …

Reconstructing the infrared spectrum of a peptide from representative conformers of the full canonical ensemble

A Kotobi, L Schwob, GB Vonbun-Feldbauer… - Communications …, 2023 - nature.com
Leucine enkephalin (LeuEnk), a biologically active endogenous opioid pentapeptide, has
been under intense investigation because it is small enough to allow efficient use of …

Experimental techniques and terminology in gas‐phase ion spectroscopy

A Pereverzev, J Roithová - Journal of Mass Spectrometry, 2022 - Wiley Online Library
This perspective gives an overview of the action spectroscopy methods for measurements of
electronic, vibrational, and rotational spectra of mass‐selected ions in the gas phase. We …

Conformations of prolyl–peptide bonds in the bradykinin 1–5 fragment in solution and in the gas phase

L Voronina, A Masson, M Kamrath… - Journal of the …, 2016 - ACS Publications
The dynamic nature of intrinsically disordered peptides makes them a challenge to
characterize by solution-phase techniques. In order to gain insight into the relation between …

Infrared Photodissociation Spectroscopy of Water-Tagged Ions with a Widely Tunable Quantum Cascade Laser for Planetary Science Applications

TM Nguyen, DC Ober, A Balaji, FW Maiwald… - Analytical …, 2024 - ACS Publications
This work presents a benchtop method for collecting the room temperature gas phase
infrared (IR) action spectra of protonated amino acids and their isomers. The adopted setup …