Mechanistic insights on age-related changes in heart-aorta-brain hemodynamic coupling using a pulse wave model of the entire circulatory system

A Aghilinejad, F Amlani… - American Journal …, 2023 - journals.physiology.org
Age-related changes in aortic biomechanics can impact the brain by reducing blood flow
and increasing pulsatile energy transmission. Clinical studies have shown that impaired …

On the longitudinal wave pumping in fluid-filled compliant tubes

A Aghilinejad, B Rogers, H Geng, NM Pahlevan - Physics of Fluids, 2023 - pubs.aip.org
This study investigates the physics of the longitudinal stretching-based wave pumping
mechanism, a novel extension of the traditional impedance pump. In its simplest form, an …

Adverse Cardiovascular effects of Nicotine delivered by Chronic Electronic cigarettes or Standard cigarettes captured by Cardiovascular intrinsic frequencies

R Alavi, W Dai, SP Mazandarani… - Journal of the …, 2024 - ahajournals.org
Background Electronic cigarettes have gained popularity as a nicotine delivery system,
which has been recommended by some as an aid to help people quit traditional smoking …

Non-invasive pressure-only aortic wave intensity evaluation using hybrid Fourier decomposition-machine learning approach

A Aghilinejad, H Wei… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Objective: The clinical significance of the wave intensity (WI) analysis for the diagnosis and
prognosis of the cardiovascular and cerebrovascular diseases is well-established. However …

Framework development for patient-specific compliant aortic dissection phantom model fabrication: magnetic resonance imaging validation and deep-learning …

A Aghilinejad, H Wei, C Bilgi… - Journal of …, 2023 - asmedigitalcollection.asme.org
Type B aortic dissection is a life-threatening medical emergency that can result in rupture of
the aorta. Due to the complexity of patient-specific characteristics, only limited information on …

A preoperative planning procedure of septal myectomy for hypertrophic obstructive cardiomyopathy using image-based computational fluid dynamics simulations and …

Z Ding, Q Liu, H Luo, M Yang, Y Zhang, S Wang… - Scientific Reports, 2024 - nature.com
Although septal myectomy is the preferred treatment for medication-refractory hypertrophic
obstructive cardiomyopathy (HOCM), the procedure remains subjective. A preoperative …

Direct 0D‐3D coupling of a lattice Boltzmann methodology for fluid–structure aortic flow simulations

H Wei, F Amlani, NM Pahlevan - International Journal for …, 2023 - Wiley Online Library
This work introduces a numerical approach and implementation for the direct coupling of
arbitrary complex ordinary differential equation‐(ODE‐) governed zero‐dimensional (0D) …

The global effect of aortic coarctation on carotid and renal pulsatile hemodynamics

D Rafiei, NM Pahlevan - PloS one, 2024 - journals.plos.org
Coarctation of the aorta (CoA) is a congenital disease characterized by the narrowing of the
aorta, typically the descending portion after the left subclavian artery. If left untreated, by the …

A machine learning approach for computation of cardiovascular intrinsic frequencies

R Alavi, Q Wang, H Gorji, NM Pahlevan - Plos one, 2023 - journals.plos.org
Analysis of cardiovascular waveforms provides valuable clinical information about the state
of health and disease. The intrinsic frequency (IF) method is a recently introduced framework …

A new methodology for determining the central pressure waveform from peripheral measurement using Fourier-based machine learning

A Aghilinejad, A Tamborini, M Gharib - Artificial Intelligence in Medicine, 2024 - Elsevier
Radial applanation tonometry is a well-established technique for hemodynamic monitoring
and is becoming popular in affordable non-invasive wearable healthcare electronics. To …