Recent progress in selective additions of organometal reagents to carbonyl compounds

M Hatano, T Miyamoto, K Ishihara - Current Organic Chemistry, 2007 - ingentaconnect.com
Carbon-carbon bond forming reactions are simple and direct methods for synthesizing the
various skeletons and the diverse structures of organic compounds. Even 100 years after the …

Enantioselective diethylzinc addition to aromatic and aliphatic aldehydes using (3R, 5R)-dihydroxypiperidine derivatives catalyst

R Roudeau, DG Pardo, J Cossy - Tetrahedron, 2006 - Elsevier
A series of chiral (3R, 5R)-dihydroxypiperidine derivatives were conveniently prepared from
trans-4-hydroxy-l-proline and applied to the catalytic enantioselective addition of diethylzinc …

[PDF][PDF] ENANTIOSELECTIVE ORGANOZINC-CATALYZED ADDITIONS TO CARBONYL COMPOUNDS–RECENT DEVELOPMENTS

V Dimitrov, M Kamenova-Nacheva - Journal of the University of …, 2009 - researchgate.net
The realization of enantioselective CC-bond forming reactions is of immense importance in
the modern organic synthesis. The global needs of pharmaceutical industry and the fast …

Asymmetric addition of diethylzinc to aldehydes catalyzed by a camphor-derived β-amino alcohol

ZL Wu, HL Wu, PY Wu, BJ Uang - Tetrahedron: Asymmetry, 2009 - Elsevier
The asymmetric addition of diethylzinc to aromatic and aliphatic aldehydes, including linear
aliphatic ones, catalyzed by 2mol% of β-amino alcohol (1S, 2R)-7, 7-dimethyl-1-morpholin-4 …

Reactions of Aldehydes and Ketones and their Derivatives

BA Murray - Organic Reaction Mechanisms 2011: An annual …, 2014 - Wiley Online Library
Carbohydrate‐based benzylidene acetals undergo reductive ring opening. 1‐β‐O‐Acyl
glucoside conjugates of phenylacetic acids have been synthesized, and their acyl migration …

The role of conformational flexibility on the catalytic activity of norbornane-derived β-, γ-and δ-amino alcohols

AG Martínez, ET Vilar, AG Fraile… - Tetrahedron …, 2007 - Elsevier
Enantiopure norbornane-based γ-amino alcohols 1–4 have been obtained from (+)-
camphor and their catalytic behaviour as chiral ligands for the enantioselective addition of …

C (10)-substituted camphors and fenchones by electrophilic treatment of 2-methylenenorbornan-1-ols: Enantiospecificity, scope, and limitations

S de la Moya Cerero, A García Martínez… - The Journal of …, 2003 - ACS Publications
Valuable chiral sources of C (10)-substituted camphors and C (10)-substituted fenchones
can be straightforwardly obtained by treatment of an appropriate, easily obtainable, camphor …

Catalytic enantioselective borane reduction of arylketones with pinene-derived amino alcohols

D Hobuß, A Baro, S Laschat, W Frey - Tetrahedron, 2008 - Elsevier
Both cis-and trans-1, 2-amino alcohols 5 and their N-alkylated derivatives 6 were prepared
from (−)-α-pinene 7 as chirality source and utilized in asymmetric borane reduction of …

Highly efficient synthesis of chiral aminoalcohols and aminodiols with camphane skeleton

MP Stoyanova, BL Shivachev, RP Nikolova… - Tetrahedron …, 2013 - Elsevier
Methylidene substituted camphor was easily epoxidized to give bridgehead oxirane-
substituted camphor in the form of two diastereoisomers, isolated in pure form. These were …

Functionalized organolithium reagents in the synthesis of chiral ligands for catalytic enantioselective addition of diethylzinc to aldehydes

GM Dobrikov, I Philipova, R Nikolova, B Shivachev… - Polyhedron, 2012 - Elsevier
Series of functionalized organolithium compounds were prepared and added to chiral
bicyclic ketones (1R-(+)-camphor analogue 2 and 1R-(−)-fenchone 3), resulting in the …