Seminal plasma: relevant for fertility?

H Rodriguez-Martinez, EA Martinez, JJ Calvete… - International Journal of …, 2021 - mdpi.com
Seminal plasma (SP), the non-cellular component of semen, is a heterogeneous composite
fluid built by secretions of the testis, the epididymis and the accessory sexual glands. Its …

Simulating nature in sperm selection for assisted reproduction

ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

Immunophenotype profile by flow cytometry reveals different subtypes of extracellular vesicles in porcine seminal plasma

I Barranco, A Alvarez-Barrientos, A Parra… - Cell Communication and …, 2024 - Springer
Background Porcine seminal plasma (SP) is endowed with a heterogeneous population of
extracellular vesicles (sEVs). This study evaluated the immunophenotypic profile by high …

The role of semen and seminal plasma in inducing large-scale genomic changes in the female porcine peri-ovulatory tract

M Álvarez-Rodríguez, CA Martinez, D Wright… - Scientific reports, 2020 - nature.com
Semen modifies the expression of genes related to immune function along the porcine
female internal genital tract. Whether other pathways are induced by the deposition of …

[HTML][HTML] Extracellular vesicles in seminal plasma: A safe and relevant tool to improve fertility in livestock?

H Rodriguez-Martinez, J Roca - Animal Reproduction Science, 2022 - Elsevier
Seminal plasma (SP) is not a pre-requisite for pregnancy. Yet, this heterogeneous,
composite SP has proven relevant for fertility, as mediator for cell-to-cell communication …

Sperm phenotypic characteristics and oviduct binding ability are altered in breeding bulls with high sperm DNA fragmentation index

P Nag, A Kumaresan, S Akshaya, A Manimaran… - Theriogenology, 2021 - Elsevier
In the present study, we standardized an in vitro oviduct explants model for cattle and
assessed the oviduct explants binding ability and phenotypic characteristics of spermatozoa …

Role and modulation of TRPV1 in mammalian spermatozoa: An Updated Review

M Ramal-Sanchez, N Bernabò, L Valbonetti… - International Journal of …, 2021 - mdpi.com
Based on the abundance of scientific publications, the polymodal sensor TRPV1 is known
as one of the most studied proteins within the TRP channel family. This receptor has been …

Ligand binding and signaling of HARE/Stabilin-2

EN Harris, F Cabral - Biomolecules, 2019 - mdpi.com
The Stabilin receptors are a two-member family in the type H class of scavenger receptors.
These dynamic receptors bind and internalize multiple ligands from the cell surface for the …

Exosomes in specific fractions of the boar ejaculate contain CD44: A marker for epididymosomes?

M Alvarez-Rodriguez, SA Ljunggren, H Karlsson… - Theriogenology, 2019 - Elsevier
Seminal plasma (SP) is a complex fluid containing proteins, peptides, enzymes, hormones
as well as extracellular vesicles (EVs). The SP interacts with spermatozoa and the inner cell …

Improving porcine in vitro fertilization output by simulating the oviductal environment

C Soriano-Úbeda, FA García-Vázquez… - Scientific Reports, 2017 - nature.com
Differences between the in vitro and in vivo environment in which fertilization occurs seem to
play a key role in the low efficiency of porcine in vitro fertilization (IVF). This work proposes …