Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Coronary artery disease (CAD) is one of the major cardiovascular diseases affecting the
global human population. This disease has been proved to be the major cause of death in …

Acute myocardial infarction (MI) inflicts massive injury to the coronary microcirculation
leading to vascular disintegration and capillary rarefication in the infarct region. Tissue …

Ischaemic heart disease is a leading cause of death worldwide. Injury to the heart is
followed by loss of the damaged cardiomyocytes, which are replaced with fibrotic scar …

The identification and production of recombinant morphogens and growth factors that play
key roles in tissue regeneration have generated much enthusiasm and numerous clinical …

The family of fibroblast growth factors (FGFs) regulates a plethora of developmental
processes, including brain patterning, branching morphogenesis and limb development …

Myocardial infarction, among other ischemic heart diseases, is the major cause of mortality
and morbidity for patients who have heart diseases. Timely reperfusion of the ischemic …

Background—The delivery of autologous cells to increase angiogenesis is emerging as a
treatment option for patients with cardiovascular disease but may be limited by the …

We recently demonstrated that marrow stromal cells (MSCs) augment collateral remodeling
through release of several cytokines such as VEGF and bFGF rather than via cell …

Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert
their pro-angiogenic activity by interacting with various endothelial cell surface receptors …