Current status of alginate in drug delivery

DM Hariyadi, N Islam - Advances in pharmacological and …, 2020 - Wiley Online Library
Alginate is one of the natural polymers that are often used in drug‐and protein‐delivery
systems. The use of alginate can provide several advantages including ease of preparation …

Nano and microparticles as potential oral vaccine carriers and adjuvants against infectious diseases

SD Jazayeri, HX Lim, K Shameli, SK Yeap… - Frontiers in …, 2021 - frontiersin.org
Mucosal surfaces are the first site of infection for most infectious diseases and oral
vaccination can provide protection as the first line of defense. Unlike systemic …

Mucosal BCG vaccination induces protective lung-resident memory T cell populations against tuberculosis

C Perdomo, U Zedler, AA Kühl, L Lozza, P Saikali… - MBio, 2016 - Am Soc Microbiol
ABSTRACT Mycobacterium bovis Bacille Calmette-Guérin (BCG) is the only licensed
vaccine against tuberculosis (TB), yet its moderate efficacy against pulmonary TB calls for …

BCG vaccination strategies against tuberculosis: updates and perspectives

M Qu, X Zhou, H Li - Human Vaccines & Immunotherapeutics, 2021 - Taylor & Francis
ABSTRACT Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against
tuberculosis (TB). However, BCG has variable efficacy and cannot completely prevent TB …

Current and new approaches for mucosal vaccine delivery

JH Rhee - Mucosal vaccines, 2020 - Elsevier
Mucosal surfaces are the interface between the host's internal milieu and the external
environment, and they have dual functions, serving as physical barriers to foreign antigens …

Immunogenic properties of Lactobacillus plantarum producing surface-displayed Mycobacterium tuberculosis antigens

K Kuczkowska, CR Kleiveland, R Minic… - Applied and …, 2017 - Am Soc Microbiol
Tuberculosis (TB) remains among the most deadly diseases in the world. The only available
vaccine against tuberculosis is the bacille Calmette-Guérin (BCG) vaccine, which does not …

Recent advances in nano/microparticle-based oral vaccines

M Li, LM Kaminskas, N Marasini - Journal of Pharmaceutical Investigation, 2021 - Springer
Background Vaccines are often recognized as one of the most cost-effective public health
interventions in controlling infectious diseases. Most pathogens infiltrate the body from …

An overview of the BCG vaccine and its future scope

P Khandelia, S Yadav, P Singh - Indian Journal of Tuberculosis, 2023 - Elsevier
Despite intense elimination efforts, tuberculosis (TB) still poses a threat to world health,
disproportionately affecting less developed and poorer countries. The Bacillus Calmette …

Induction of protective immunity by a single low dose of a master cell bank cGMP-rBCG-P vaccine against the human metapneumovirus in mice

JA Soto, NMS Gálvez, GA Pacheco… - Frontiers in cellular …, 2021 - frontiersin.org
Human metapneumovirus (hMPV) is an emergent virus, which mainly infects the upper and
lower respiratory tract epithelium. This pathogen is responsible for a significant portion of …

Plant production of a virus-like particle-based vaccine candidate against porcine reproductive and respiratory syndrome

JT VanderBurgt, O Harper, CP Garnham… - Frontiers in Plant …, 2023 - frontiersin.org
Porcine reproductive and respiratory syndrome (PRRS) is a disease leading to spontaneous
abortions and stillbirths in sows and lowered life quality and expectancy in growing pigs …