Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)
Plants in the genus Tripterygium, such as Tripterygium wilfordii Hook. f., have a long history
of use in traditional Chinese medicine. In recent years there has been considerable interest …
of use in traditional Chinese medicine. In recent years there has been considerable interest …
Terpenoids and breast cancer chemoprevention
T Rabi, A Bishayee - Breast cancer research and treatment, 2009 - Springer
Cancer chemoprevention is defined as the use of natural or synthetic agents that reverse,
suppress or arrest carcinogenic and/or malignant phenotype progression towards invasive …
suppress or arrest carcinogenic and/or malignant phenotype progression towards invasive …
Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria
CC Wu, ML Chan, WY Chen, CY Tsai, FR Chang… - Molecular cancer …, 2005 - AACR
Pristimerin, a naturally occurring triterpenoid, has been shown to cause cytotoxicity in
several cancer cell lines. However, the mechanism for the cytotoxic effect of pristimerin was …
several cancer cell lines. However, the mechanism for the cytotoxic effect of pristimerin was …
Protective effect of pristimerin against LPS-induced acute lung injury in mice
Pristimerin (Pris) is a triterpenoid derivative obtained from Celastraceae and
Hippocrateaceae families. This compound has been extensively tested for its potent anti …
Hippocrateaceae families. This compound has been extensively tested for its potent anti …
Pristimerin inhibits LPS-triggered neurotoxicity in BV-2 microglia cells through modulating IRAK1/TRAF6/TAK1-mediated NF-κB and AP-1 signaling pathways in vitro
B Hui, L Zhang, Q Zhou, L Hui - Neurotoxicity research, 2018 - Springer
Microglia plays a prominent role in the brain's inflammatory response to injury or infection by
migrating to affected locations and secreting inflammatory molecules. However …
migrating to affected locations and secreting inflammatory molecules. However …
Antitumoral, mutagenic and (anti) estrogenic activities of tingenone and pristimerin
JPM Gomes, CRP Cardoso, EA Varanda… - Revista Brasileira de …, 2011 - SciELO Brasil
Cancer constitutes the second main mortality cause in the world, after cardiovascular
diseases. In spite of the progresses in the chemotherapeutics treatments, many patients fail …
diseases. In spite of the progresses in the chemotherapeutics treatments, many patients fail …
Pristimerin, a natural anti-tumor triterpenoid, inhibits LPS-induced TNF-α and IL-8 production through down-regulation of ROS-related classical NF-κB pathway in THP …
B Hui, X Yao, Q Zhou, Z Wu, P Sheng… - International …, 2014 - Elsevier
Pristimerin, a naturally occurring quinonemethide triterpenoid compound, is known to exert a
variety of pharmacological activities. In the present study, we investigated the molecular …
variety of pharmacological activities. In the present study, we investigated the molecular …
Selective anti-cancer effects of palm phytonutrients on human breast cancer cells
R Loganathan, AK Radhakrishnan, KR Selvaduray… - RSC Advances, 2015 - pubs.rsc.org
Palm oil contains a number of phytonutrients. To date, most of the studies using palm
phytonutrients have focused on palm vitamin E. The objective of this study was to compare …
phytonutrients have focused on palm vitamin E. The objective of this study was to compare …