Protein S-nitrosylation in health and disease: a current perspective
Protein S-nitrosylation constitutes a large part of the ubiquitous influence of nitric oxide on
cellular signal transduction and accumulating evidence indicates important roles for S …
cellular signal transduction and accumulating evidence indicates important roles for S …
Nitric oxide signaling in T cell-mediated immunity
A García-Ortiz, JM Serrador - Trends in molecular medicine, 2018 - cell.com
Nitric oxide (NO) is a key messenger in the pathogenesis of inflammation, linking innate and
adaptive immunity. By targeting signaling molecules, NO from inducible NO synthase (iNOS) …
adaptive immunity. By targeting signaling molecules, NO from inducible NO synthase (iNOS) …
Nitric oxide signaling: classical, less classical, and nonclassical mechanisms
Although nitric oxide (NO) was identified more than 150 years ago and its effects were
clinically tested in the form of nitroglycerine, it was not until the decades of 1970–1990 that it …
clinically tested in the form of nitroglycerine, it was not until the decades of 1970–1990 that it …
Dual targeting of the thioredoxin and glutathione systems in cancer and HIV
M Benhar, IL Shytaj, JS Stamler… - The Journal of clinical …, 2016 - Am Soc Clin Investig
Although the use of antioxidants for the treatment of cancer and HIV/AIDS has been
proposed for decades, new insights gained from redox research have suggested a very …
proposed for decades, new insights gained from redox research have suggested a very …
Thioredoxin and Thioredoxin Reductase in Relation to Reversible S-Nitrosylation
R Sengupta, A Holmgren - Antioxidants & redox signaling, 2013 - liebertpub.com
Significance: Nitric oxide (NO) regulates a diverse range of cellular processes, including
vasodilation, neurotransmission, and antimicrobial and anti-tumor activities. S-nitrosylation …
vasodilation, neurotransmission, and antimicrobial and anti-tumor activities. S-nitrosylation …
Monomeric C‐reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype‐dependent pattern: A risk factor for Alzheimer's disease?
In chronic peripheral inflammation, endothelia in brain capillary beds could play a role for
the apolipoprotein E4 (ApoE4)‐mediated risk for Alzheimer's disease (AD) risk. Using …
the apolipoprotein E4 (ApoE4)‐mediated risk for Alzheimer's disease (AD) risk. Using …
Specificity in S-nitrosylation: a short-range mechanism for NO signaling?
A Martinez-Ruiz, IM Araújo… - Antioxidants & redox …, 2013 - liebertpub.com
Significance: Nitric oxide (NO) classical and less classical signaling mechanisms (through
interaction with soluble guanylate cyclase and cytochrome c oxidase, respectively) operate …
interaction with soluble guanylate cyclase and cytochrome c oxidase, respectively) operate …
Thioredoxin 1-mediated post-translational modifications: reduction, transnitrosylation, denitrosylation, and related proteomics methodologies
Despite the significance of redox post-translational modifications (PTMs) in regulating
diverse signal transduction pathways, the enzymatic systems that catalyze reversible and …
diverse signal transduction pathways, the enzymatic systems that catalyze reversible and …
[HTML][HTML] Nitric oxide and hydrogen sulfide regulation of ischemic vascular growth and remodeling
Ischemic vascular remodeling occurs in response to stenosis or arterial occlusion leading to
a change in blood flow and tissue perfusion. Altered blood flow elicits a cascade of …
a change in blood flow and tissue perfusion. Altered blood flow elicits a cascade of …
[HTML][HTML] The Golgi complex: a hub of the secretory pathway
The Golgi complex plays a central role in protein secretion by regulating cargo sorting and
trafficking. As these processes are of functional importance to cell polarity, motility, growth …
trafficking. As these processes are of functional importance to cell polarity, motility, growth …