[HTML][HTML] Gut microbiota dysbiosis, oxidative stress, inflammation, and epigenetic alterations in metabolic diseases

H Mostafavi Abdolmaleky, JR Zhou - Antioxidants, 2024 - mdpi.com
Gut dysbiosis, resulting from an imbalance in the gut microbiome, can induce excessive
production of reactive oxygen species (ROS), leading to inflammation, DNA damage …

Gut aging: a wane from the normal to repercussion and gerotherapeutic strategies

JK Abankwah, Y Wang, J Wang, SE Ogbe, L Dal Pozzo… - Heliyon, 2024 - cell.com
Globally, age-related diseases represent a significant public health concern among the
elderly population. In aging, healthy organs and tissues undergo structural and functional …

[HTML][HTML] Flavonoids-Enriched Vegetal Extract Prevents the Activation of NFκB Downstream Mechanisms in a Bowel Disease In Vitro Model

P Corbetta, E Lonati, S Pagliari, M Mauri… - International Journal of …, 2024 - mdpi.com
Inflammatory bowel disease (IBD) incidence has increased in the last decades due to
changes in dietary habits. IBDs are characterized by intestinal epithelial barrier disruption …

Glibenclamide-Loaded Engineered Nanovectors (GNVs) Modulate Autophagy and NLRP3-Inflammasome Activation

M Saresella, CP Zoia, F La Rosa, C Bazzini, G Sala… - Pharmaceuticals, 2023 - mdpi.com
Activation of the NLRP3 inflammasome in response to either exogenous (PAMPs) or
endogenous (DAMPs) stimuli results in the production of IL-18, caspase-1 and IL-1β. These …

Glibenclamide-Loaded Nanoparticles Reduce NLRP3 Inflammasome Activation and Modulate miR-223-3p/miR-7-1-5p Expression in THP-1 Cells

R Mancuso, LA Citterio, S Agostini, I Marventano… - Pharmaceuticals, 2023 - mdpi.com
The anti-hyperglycemic drug glibenclamide (Glb) might represent an interesting therapeutic
option in human neurodegenerative diseases because of its anti-inflammatory activity and …

Targeting programmed cell death in inflammatory bowel disease through natural products: New insights from molecular mechanisms to targeted therapies

M Wang, Z Wang, Z Li, Y Qu, J Zhao… - Phytotherapy …, 2024 - Wiley Online Library
Inflammatory bowel disease (IBD) is an autoimmune disorder primarily characterized by
intestinal inflammation and recurrent ulceration, leading to a compromised intestinal barrier …

Microbiome-based therapies for Parkinson's disease

M Alam, K Abbas, M Mustafa, N Usmani… - Frontiers in Nutrition, 2024 - frontiersin.org
The human gut microbiome dysbiosis plays an important role in the pathogenesis of
Parkinson's disease (PD). The bidirectional relationship between the enteric nervous system …

[PDF][PDF] ENFLAMATUAR BAĞIRSAK HASTALIĞI VE TIBBİ BİTKİLER: GÜNCEL BİR GÖZDEN GEÇİRME.

E BAYIR, G ELGİN CEBE - Journal of Faculty of Pharmacy of …, 2024 - researchgate.net
Amaç: Enflamatuar bağırsak hastalığı (EBH), ülserasyon, kanama, sıvı ve elektrolit kaybı ile
karakterize, atak ve remisyon dönemlerinden oluşan gastrointestinal sistemin (GİS) kronik …

ENFLAMATUAR BAĞIRSAK HASTALIĞI VE TIBBİ BİTKİLER: GÜNCEL BİR GÖZDEN GEÇİRME

E Bayır, GE Cebe - Journal of Faculty of Pharmacy of Ankara University - dergipark.org.tr
Amaç: Enflamatuar bağırsak hastalığı (EBH), ülserasyon, kanama, sıvı ve elektrolit kaybı ile
karakterize, atak ve remisyon dönemlerinden oluşan gastrointestinal sistemin (GİS) kronik …