Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities
The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …
Targeting heat shock proteins in cancer
G Jego, A Hazoumé, R Seigneuric, C Garrido - Cancer letters, 2013 - Elsevier
Heat shock proteins (HSPs) HSP27, HSP70 and HSP90 are powerful chaperones. Their
expression is induced in response to a wide variety of physiological and environmental …
expression is induced in response to a wide variety of physiological and environmental …
Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death
J Acunzo, M Katsogiannou, P Rocchi - … journal of biochemistry & cell biology, 2012 - Elsevier
Hsp27, αB-crystallin and HSP22 are ubiquitous small heat shock proteins (sHsp) whose
expression is induced in response to a wide variety of unfavorable physiological and …
expression is induced in response to a wide variety of unfavorable physiological and …
Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update
DR Ciocca, AP Arrigo, SK Calderwood - Archives of toxicology, 2013 - Springer
Heat shock proteins (HSP) are a subset of the molecular chaperones, best known for their
rapid and abundant induction by stress. HSP genes are activated at the transcriptional level …
rapid and abundant induction by stress. HSP genes are activated at the transcriptional level …
Small heat shock proteins in cancer therapy and prognosis
A Zoubeidi, M Gleave - The international journal of biochemistry & cell …, 2012 - Elsevier
Hsp27 and clusterin (CLU are stress-activated small heat shock proteins that are up-
regulated in many cancers where they play important roles in stress-induced protein …
regulated in many cancers where they play important roles in stress-induced protein …
[HTML][HTML] The role of Hsp27 in chemotherapy resistance
M Lampros, N Vlachos, S Voulgaris, GA Alexiou - Biomedicines, 2022 - mdpi.com
Heat shock protein (Hsp)-27 is a small-sized, ATP-independent, chaperone molecule that is
overexpressed under conditions of cellular stress such as oxidative stress and heat shock …
overexpressed under conditions of cellular stress such as oxidative stress and heat shock …
Heat shock proteins: cell protection through protein triage
D Lanneau, G Wettstein, P Bonniaud… - The Scientific World …, 2010 - Wiley Online Library
Heat shock proteins (HSPs) are chaperones that catalyze the proper folding of nascent
proteins and the refolding of denatured proteins. The ubiquitin‐proteasome system is an …
proteins and the refolding of denatured proteins. The ubiquitin‐proteasome system is an …
[HTML][HTML] Human small heat shock proteins: protein interactomes of homo-and hetero-oligomeric complexes: an update
AP Arrigo - FEBS letters, 2013 - Elsevier
Small heat shock proteins (sHsps) regulate a large number of fundamental cellular
processes and are involved in many pathological diseases. They share complex …
processes and are involved in many pathological diseases. They share complex …
Regulation of apoptosis by heat shock proteins
Thermotolerance, the acquired resistance of cells to stress, is a well‐established
phenomenon. Studies of the key mediators of this response, the heat shock proteins (HSPs) …
phenomenon. Studies of the key mediators of this response, the heat shock proteins (HSPs) …
The role of heat shock proteins in metastatic colorectal cancer: A review
Heat shock proteins (HSPs) are a large molecular chaperone family classified by their
molecular weights, including HSP27, HSP40, HSP60, HSP70, HSP90, and HSP110. HSPs …
molecular weights, including HSP27, HSP40, HSP60, HSP70, HSP90, and HSP110. HSPs …