Malnutrition has historically been researched and addressed within two distinct silos,
focusing either on undernutrition, food insecurity, and micronutrient deficiencies, or on …

Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …

Exposures to adverse environments, both psychosocial and physicochemical, are prevalent
and consequential across a broad range of childhood populations. Such adversity …

Biological embedding occurs when life experience alters biological processes to affect later
life health and well-being. Although extensive correlative data exist supporting the notion …

Longstanding racial/ethnic inequalities in morbidity and mortality persist in the United States.
Although the determinants of health inequalities are complex, social and structural factors …

Policy Points A large body of scientific work examines the mechanisms through which social
determinants of health (SDOH) shape health inequities. However, the nuances described in …

Chronic inflammation contributes to the onset and progression of cardiovascular disease
and other degenerative diseases of aging. But does it have to? This article considers the …

Despite their unique histories, environments, and lifestyles, historically subjugated
populations consistently show poorer health outcomes compared to the general population …

Pathogen-imposed selection pressures have been paramount during human evolution.
Detecting such selection signatures in ancient and modern human genomes can thus help …

Immune function is an energetically costly physiological activity that potentially diverts
calories away from less immediately essential life tasks. Among developing organisms, the …