INTRODUCTION von Willebrand Disease (VWD), the most common inherited bleeding
disorder, is defined by decreased activity of von Willebrand Factor (VWF) activity in the …

Partial quantitative deficiency of plasma von Willebrand factor (VWF) is responsible for the
majority of cases of von Willebrand disease (VWD), the most common inherited human …

Recent studies have demonstrated that only 30% of patients referred for assessment of a
possible bleeding tendency will eventually be diagnosed with a mild bleeding disorder …

Background In a large proportion of patients with a mild to moderate bleeding tendency no
diagnosis can be established (bleeding of unknown cause, BUC). Objectives To investigate …

Von Willebrand disease (VWD) is an inherited bleeding disorder caused by quantitative or
qualitative deficiencies in von Willebrand factor (VWF). People with VWD may experience …

von Willebrand disease (VWD) and haemophilia represent common inherited or acquired
bleeding disorders, but many laboratories and clinicians continue to struggle with their …

Introduction The diagnostic trajectory of patients with increased bleeding tendency can be
very costly and time‐consuming. In addition, previous studies have shown that half of these …

There are limited observational studies among children diagnosed with von Willebrand
Disease (VWD). We analyzed differences in bleeding characteristics by sex and type of …

Platelets respond to vessel wall injury by forming a primary hemostatic plug to arrest blood
loss. Hemostatic plug formation is complex, and involves platelet adhesion to the …

Introduction von Willebrand disease (VWD) is the most common inherited bleeding disorder
and may alternatively arise as an acquired condition (AVWS). These represent deficiency …