Dynamic movement and turnover of extracellular matrices during tissue development and maintenance

Y Matsubayashi - Fly, 2022 - Taylor & Francis
Extracellular matrices (ECMs) are essential for the architecture and function of animal
tissues. ECMs have been thought to be highly stable structures; however, too much stability …

Quantitative and Kinetic Proteomics Reveal ApoE Isoform-dependent Proteostasis Adaptations in Mouse Brain

NR Zuniga, NE Earls, AEA Denos… - PLOS Computational …, 2024 - journals.plos.org
Apolipoprotein E (ApoE) polymorphisms modify the risk of Alzheimer's disease with ApoE4
strongly increasing and ApoE2 modestly decreasing risk relative to the control ApoE3. To …

[PDF][PDF] 5.1 Chapter Summary

N Zuniga, RS Burlett, LM Patil… - Using Quantitative …, 2023 - scholarsarchive.byu.edu
46 ontologies. We found that ApoE4 and ApoE2 both lead to modified regulation of
mitochondrial membrane proteins. In ApoE4 mice this regulation is not cohesive suggesting …