Lipids are a complex and diverse group of molecules with crucial roles in many
physiological processes, as well as in the onset, progression, and maintenance of cancers …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in
the world. Metabolic reprogramming is considered a new hallmark of cancer, but it remains …

Liver metastasis is highly aggressive and treatment-refractory, partly due to macrophage-
mediated immune suppression. Understanding the mechanisms leading to functional …

Cancer progression results from activation of various signaling networks. Among these,
PI3K/Akt signaling contributes to proliferation, invasion, and inhibition of apoptosis …

CD36, located on the cell membrane, transports fatty acids in response to dietary fat. It is a
critical fatty acid sensor and regulator of lipid metabolism. The interaction between CD36 …

Cluster of differentiation 36 (CD36) is a cell surface scavenger receptor that plays critical
roles in many different types of cancer, notably breast, brain, and ovarian cancers. While it is …

CD36 is highly expressed in diverse tumor types and its expression correlates with
advanced stages, poor prognosis, and reduced survival. In cancer cells, CD36: 1) increases …

Background Peritoneal metastasis (PM) occurs frequently in patients with gastric cancer
(GC) and confers poor survival. Lipid metabolism acts as a non‐negligible regulator in …

CSCs (Cancer stem cells) with distinct metabolic features are considered to cause HCC
(hepatocellular carcinoma) initiation, metastasis and therapeutic resistance. Here, we …

Tumor cells need to rewire their metabolic pathways to regulate the nutrient uptake and
metabolism to sustain the energy production. Lipids are important components of energy …