Synthesis and transformations of NH‐sulfoximines

M Andresini, A Tota, L Degennaro… - … –A European Journal, 2021 - Wiley Online Library
Recent years have seen a marked increase in the occurrence of sulfoximines in the
chemical sciences, often presented as valuable motifs for medicinal chemistry. This has …

N− H and C− H functionalization of sulfoximine: recent advancement and prospects

P Ghosh, B Ganguly, S Das - Asian Journal of Organic …, 2020 - Wiley Online Library
Sulfoximine and its congeners are a versatile class of structural motifs widely found in a
plethora of pharmaceutical compounds and crop protection industries due to their …

Synthesis of NH-sulfoximines from sulfides by chemoselective one-pot N-and O-transfers

A Tota, M Zenzola, SJ Chawner… - Chemical …, 2017 - pubs.rsc.org
Direct synthesis of NH-sulfoximines from sulfides has been achieved through O and NH
transfer in the same reaction, occurring with complete selectivity. The reaction is mediated …

Utilization of methylarenes as versatile building blocks in organic synthesis

R Vanjari, KN Singh - Chemical Society Reviews, 2015 - pubs.rsc.org
The development of practical and efficient methods for C–C and C–X bond formation has
attracted a great deal of current attention with the advent of C–H functionalization reactions …

Straightforward strategies for the preparation of NH-sulfoximines: a serendipitous story

JA Bull, L Degennaro, R Luisi - Synlett, 2017 - thieme-connect.com
Sulfoximines are emerging as valuable new isosteres for use in medicinal chemistry, with
the potential to modulate physicochemical properties. Recent developments in synthetic …

Copper-Catalyzed Esterification of Alkylbenzenes with Cyclic Ethers and Cycloalkanes via C(sp3)–H Activation Following Cross-Dehydrogenative Coupling

SK Rout, S Guin, W Ali, A Gogoi, BK Patel - Organic letters, 2014 - ACS Publications
A copper-catalyzed cross-dehydrogenative coupling strategy has been developed for the
synthesis of two classes of esters from simple solvents. The reaction of methylarenes with …

Dual roles of sulfonyl hydrazides: a three-component reaction to construct fully substituted pyrazoles using TBAI/TBHP

J Zhang, Y Shao, H Wang, Q Luo, J Chen, D Xu… - Organic …, 2014 - ACS Publications
A mild and rapid approach has been developed for the construction of fully substituted
pyrazoles using TBAI as a catalyst and TBHP as an oxidant, in which tosylhydrazide …

Copper-catalyzed oxidative C (sp 3)–H/N–H coupling of sulfoximines and amides with simple alkanes via a radical process

F Teng, S Sun, Y Jiang, JT Yu, J Cheng - Chemical Communications, 2015 - pubs.rsc.org
A copper-catalyzed oxidative C (sp3)–H/N–H coupling of sulfoximines with simple alkanes
was developed. This protocol involved C (sp3)–N bond formation via a radical pathway and …

N-Trifluoromethylthiolated Sulfoximines

C Bohnen, C Bolm - Organic letters, 2015 - ACS Publications
Air-and moisture-stable N-trifluoromethylthio sulfoximines have been prepared from N–H-
sulfoximines via the corresponding N–Br derivatives in excellent yields. The two-step …

Iodine-Promoted Sulfoximidation of Cinnamic Acids via Oxidative C═ C Bond Cleavage

P Rahman, N Chakraborty, BK Patel… - The Journal of …, 2024 - ACS Publications
An iodine-promoted C═ C bond cleavage with concomitant decarboxylation and cross-
coupling between cinnamic acids and NH-sulfoximines has been developed. This reaction …