Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and …

The concept of cell death has been expanded beyond apoptosis and necrosis to additional
forms, including necroptosis, pyroptosis, autophagy, and ferroptosis. These cell death …

Selective autophagy relies on soluble or membrane-bound cargo receptors that recognize
cargo and bring about autophagosome formation at the cargo. The cargo-bound receptors …

Macroautophagy (herein referred to as autophagy) is an evolutionary ancient mechanism
that culminates with the lysosomal degradation of superfluous or potentially dangerous …

Autophagy is a catabolic process for unnecessary or dysfunctional cytoplasmic contents by
lysosomal degradation pathways. Autophagy is implicated in various biological processes …

Evolutionarily conserved across eukaryotic cells, macroautophagy (herein autophagy) is an
intracellular catabolic degradative process targeting damaged and superfluous cellular …

An accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) leads
to stress conditions. To mitigate such circumstances, stressed cells activate a homeostatic …

Autophagy is a primarily degradative pathway that takes place in all eukaryotic cells. It is
used for recycling cytoplasm to generate macromolecular building blocks and energy under …

Significance: Autophagy is a highly conserved eukaryotic cellular recycling process.
Through the degradation of cytoplasmic organelles, proteins, and macromolecules, and the …

Autophagy is a conserved intracellular pathway that delivers cytoplasmic contents to
lysosomes for degradation via double-membrane autophagosomes. Autophagy substrates …