Over the past decade, the global scientific community have begun to recognize the
unmatched value of an extraordinary drug, ivermectin, that originates from a single microbe …

This review summarises more than a century of research on onchocerciasis, also known as
river blindness, and its control. River blindness is an infection caused by the tissue filaria …

Background Onchocerciasis is a disease caused by infection with Onchocerca volvulus,
which is transmitted to humans via the bite of several species of black fly, and is responsible …

Background High onchocerciasis transmission predisposes endemic communities to a high
epilepsy burden. The 4· 4% epilepsy prevalence documented in 2018 in Maridi, South …

Abstract Background The African Programme for Onchocerciasis Control (APOC) was
created in 1995 to establish community-directed treatment with ivermectin (CDTi) in order to …

Model-based Geostatistics for Global Public Health: Methods and Applications provides an
introductory account of model-based geostatistics, its implementation in open-source …

The use of alternative (or complementary) treatment strategies (ATSs) ie differing from
annual community-directed treatment with ivermectin (CDTI) is required in some African foci …

Background microRNAs (miRNAs), a class of short, non-coding RNA can be found in a
highly stable, cell-free form in mammalian body fluids. Specific miRNAs are secreted by …

River blindness (onchocerciasis) causes severe itching, skin lesions, and vision impairment
including blindness. More than 99% of all current cases are found in sub-Saharan Africa …

Background WHO has proposed elimination of transmission of onchocerciasis (river
blindness) by 2030. More than 99% of cases of onchocerciasis are in sub-Saharan Africa …