Sexually transmitted diseases constitute major health issues and their prevention and
treatment continue to challenge the health care systems worldwide. Animal models are …

Chlamydial infections lead to a number of clinically relevant diseases and induce significant
morbidity in human populations. It is generally understood that certain components of the …

All Chlamydia species are obligate intracellular bacteria that undergo a unique biphasic
developmental cycle strictly in the lumen of a membrane bound compartment, the inclusion …

International efforts in developing a vaccine against Chlamydia trachomatis have
highlighted the need for novel immunization strategies for the induction of genital immunity …

Transposon mutagenesis is a widely applied and powerful genetic tool for the discovery of
genes associated with selected phenotypes. Chlamydia trachomatis is a clinically …

Sexually transmitted Chlamydia trachomatis causes infertility, and because almost 90% of
infections are asymptomatic, a vaccine is required for its eradication. Mathematical modeling …

Chlamydiosis is the most documented and serious disease of koalas, characterized by
ocular, urinary, and reproductive lesions. Since little attention has been paid to the …

With approximately 131 million new genital tract infections occurring each year, Chlamydia
is the most common sexually transmitted bacterial pathogen worldwide. Male and female …

Chlamydia muridarum actively grows in murine mucosae and is a representative model of
human chlamydial genital tract disease. In contrast, C. trachomatis infections in mice are …

Antibodies can have a protective but non‐essential role in natural chlamydial infections
dependent on antigen specificity and antibody isotype. IgG is the dominant antibody in both …