Activation of STAT and SMAD signaling induces hepcidin re-expression as a therapeutic target for β-Thalassemia patients
Iron homeostasis is regulated by hepcidin, a hepatic hormone that controls dietary iron
absorption and plasma iron concentration. Hepcidin binds to the only known iron export …
absorption and plasma iron concentration. Hepcidin binds to the only known iron export …
HBB gene mutations and their pathological impacts on HbE/β-Thalassaemia in Kuala Terengganu, Malaysia
Background: β-thalassaemia is a disorder caused by mutations in the β-globin gene, leading
to defective production of haemoglobins (Hb) and red blood cells (RBCs). It is characterised …
to defective production of haemoglobins (Hb) and red blood cells (RBCs). It is characterised …
Reduced hepcidin expression enhances iron overload in patients with HbE/β-thalassemia: Α comparative cross-sectional study
Iron homeostasis is regulated by hepcidin (HEPC) that controls the dietary iron absorption
and iron recycling. HEPC deficiency contributes to iron overload in β-thalassemia patients …
and iron recycling. HEPC deficiency contributes to iron overload in β-thalassemia patients …
Gene‒environment interaction effect of hypothalamic‒pituitary‒adrenal axis gene polymorphisms and job stress on the risk of sleep disturbances
M Zhao, Y Wang, Y Zeng, H Huang, T Xu, B Liu, C Wu… - PeerJ, 2024 - peerj.com
Background Studies have shown that chronic exposure to job stress may increase the risk of
sleep disturbances and that hypothalamic‒pituitary‒adrenal (HPA) axis gene …
sleep disturbances and that hypothalamic‒pituitary‒adrenal (HPA) axis gene …
Genetic background studies of eight common beta thalassemia mutations in Thailand using β-globin gene haplotype and phylogenetic analysis
R Karnpean, W Tepakhan, P Suankul, S Thingphom… - Genes, 2022 - mdpi.com
Single nucleotide polymorphisms are informative for haplotype analysis associated with
genetic background and clinical linkage studies of β-thalassemia mutations. Hence, the aim …
genetic background and clinical linkage studies of β-thalassemia mutations. Hence, the aim …
Xác định các biến thể gen HBB ở người bệnh β-thalassemia tại Viện Huyết học-Truyền máu Trung ương
PTT Phượng, DQ Chính, NTN Bình… - Tạp chí Nghiên cứu …, 2024 - tapchinghiencuuyhoc.vn
Tóm tắt β-thalassemia là bệnh lý huyết học di truyền đơn gen phổ biến nhất trên thế giới. Để
xác định các biến thể gen HBB ở 224 người bệnh β-thalassemia, DNA được tách từ máu …
xác định các biến thể gen HBB ở 224 người bệnh β-thalassemia, DNA được tách từ máu …