Recent advances in polymeric drug delivery systems

YK Sung, SW Kim - Biomaterials Research, 2020 - spj.science.org
Background Polymeric drug delivery systems have been achieved great development in the
last two decades. Polymeric drug delivery has defined as a formulation or a device that …

Sulfur chemistry in polymer and materials science

H Mutlu, EB Ceper, X Li, J Yang… - Macromolecular …, 2019 - Wiley Online Library
Sulfur and its functional groups are major players in an area of exciting research taking
place in modern polymer and materials science, both in academia and industry. In fact …

Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity

KA Whitehead, JR Dorkin, AJ Vegas, PH Chang… - Nature …, 2014 - nature.com
One of the most significant challenges in the development of clinically viable delivery
systems for RNA interference therapeutics is to understand how molecular structures …

Biodegradable polymers for gene-delivery applications

CK Chen, PK Huang, WC Law, CH Chu… - International journal …, 2020 - Taylor & Francis
Gene-based therapies have emerged as a new modality for combating a myriad of currently
incurable diseases. However, the fragile nature of gene therapeutics has significantly …

[HTML][HTML] A reactive oxygen species (ROS)-responsive polymer for safe, efficient, and targeted gene delivery in cancer cells

MS Shim, Y Xia - Angewandte Chemie (International ed. in English …, 2013 - ncbi.nlm.nih.gov
The high intracellular oxidative stress in a cancer cell is a biologically relevant stimulus for
efficient intracellular delivery of therapeutic genes. In this study, reactive oxygen species …

Reduction-sensitive polymers and bioconjugates for biomedical applications

F Meng, WE Hennink, Z Zhong - Biomaterials, 2009 - Elsevier
Reduction-sensitive biodegradable polymers and conjugates have emerged as a
fascinating class of biomedical materials that can be elegantly applied for intracellular …

Poly (disulfide) s: from synthesis to drug delivery

R Zhang, T Nie, Y Fang, H Huang, J Wu - Biomacromolecules, 2021 - ACS Publications
Bioresponsive polymers have been widely used in drug delivery because of their
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …

Dendrimers as carriers for delivery of chemotherapeutic agents

SH Medina, MEH El-Sayed - Chemical reviews, 2009 - ACS Publications
Dendrimers are a family of nanosized, three-dimensional polymers characterized by a
unique tree-like branching architecture and compact spherical geometry in solution (Figure …

Bioreducible polymers for gene silencing and delivery

S Son, R Namgung, J Kim, K Singha… - Accounts of chemical …, 2012 - ACS Publications
Polymeric gene delivery vectors show great potential for the construction of the ideal gene
delivery system. These systems harness their ability to incorporate versatile functional traits …

Designed to Degrade: Tailoring Polyesters for Circularity

CV Aarsen, A Liguori, R Mattsson… - Chemical …, 2024 - ACS Publications
A powerful toolbox is needed to turn the linear plastic economy into circular. Development of
materials designed for mechanical recycling, chemical recycling, and/or biodegradation in …