Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for …

A Rassi Jr, JA Marin, A Rassi - Memórias do Instituto Oswaldo Cruz, 2017 - SciELO Brasil
Chagas cardiomyopathy is the most frequent and most severe manifestation of chronic
Chagas disease, and is one of the leading causes of morbidity and death in Latin America …

[HTML][HTML] Chagas heart disease: pathophysiologic mechanisms, prognostic factors and risk stratification

A Rassi Jr, A Rassi, JA Marin-Neto - Memorias do Instituto Oswaldo …, 2009 - SciELO Brasil
Chagas heart disease (CHD) results from infection with the protozoan parasite
Trypanosoma cruzi and is the leading cause of infectious myocarditis worldwide. It poses a …

Congenital parasitic infections: a review

Y Carlier, C Truyens, P Deloron, F Peyron - Acta tropica, 2012 - Elsevier
This review defines the concepts of maternal–fetal (congenital) and vertical transmissions
(mother-to-child) of pathogens and specifies the human parasites susceptible to be …

Chagas disease: a role for autoimmunity?

RL Tarleton - Trends in parasitology, 2003 - cell.com
Despite many years of investigation and discussion, the cause of disease in chronic
Trypanosoma cruzi infection remains a hotly debated topic. The primary point of contention …

I Latin American Guideline for the diagnosis and treatment of Chagas' heart disease

JP Andrade, JA Marin-Neto, AAV Paola, F Vilas-Boas… - 2011 - SciELO Brasil
In 200581, the endemic area at risk for vectorial transmission of CD in Latin America
comprised 19 countries, and involved 108,595,000 people. In 1950, actions against the …

I Diretriz Latino-Americana para o diagnóstico e tratamento da cardiopatia chagásica

JP Andrade, JA Marin-Neto, AAV Paola, F Vilas-Boas… - 2011 - SciELO Brasil
Em 200581, a área endêmica com risco de transmissão vetorial da DC na América Latina
englobava 19 países, com 108.595. 000 pessoas expostas ao risco. Em 1950, iniciaramse …

Maternal–fetal transmission of Trypanosoma cruzi

Y Carlier, C Truyens - American Trypanosomiasis, 2010 - Elsevier
Publisher Summary Maternal fetal transmission of T. cruzi can have severe outcomes by
compromising survival and fetal/neonatal growth, and/or can lead to severe clinical forms of …

Therapy, diagnosis and prognosis of chronic Chagas disease: insight gained in Argentina

S Sosa-Estani, R Viotti, EL Segura - Memórias do Instituto Oswaldo …, 2009 - SciELO Brasil
The purpose of this review is to describe research findings regarding chronic Chagas
disease in Argentina that have changed the standards of care for patients with Trypanosoma …

Mechanisms of pathogenesis in Chagas disease

F Kierszenbaum - Acta Parasitologica, 2007 - degruyter.com
Chagas disease, caused by the obligate unicellular parasite Trypanosoma cruzi, presents
itself in a diverse collection of clinical manifestations, ranging from severe, fatal heart and …

Chagas disease

A Rassi, A Rassi, JA Marin-Neto - Neglected Tropical Diseases-Latin …, 2015 - Springer
Abstract In 1909, the Brazilian physician Carlos Chagas described a new pathogen―
Trypanosoma cruzi―and an entirely new disease to the scientific community that was …