Osteoarthritis is a painful joint disease characterized by progressive degeneration of the
articular cartilage as well as associated changes to the subchondral bone, synovium, and …

Chondrocytes in articular cartilage are surrounded by a narrow pericellular matrix (PCM)
that is both biochemically and biomechanically distinct from the extracellular matrix (ECM) of …

Virtual representations of the knee joint can provide clinicians, scientists, and engineers the
tools to explore mechanical functions of the knee and its tissue structures in health and …

Computational mechanics has been advanced in every area of orthopedic biomechanics.
The objective of this paper is to provide a general review of the computational models used …

Osteoarthritis (OA), a degenerative joint disease, is the most common chronic condition of
the joints, which cannot be prevented effectively. Computational modeling of joint …

Advances in computational mechanics, constitutive modeling, and techniques for subject-
specific modeling have opened the door to patient-specific simulation of the relationships …

Background: Nutrition informatics has become a novel approach for registered dietitians to
practice in this field and make a profit for health care. Recommendation systems considered …

Articular cartilage experiences significant mechanical loads during daily activities. Healthy
cartilage provides the capacity for load bearing and regulates the mechanobiological …

Recent explorations of knee biomechanics have benefited from computational modeling,
specifically leveraging advancements in finite element analysis and rigid body dynamics of …

Mechanical signals experienced by chondrocytes (articular cartilage cells) modulate cell
synthesis and cartilage health. Multi-scale modeling can be used to study how forces are …