Advances of antimicrobial peptide‐based biomaterials for the treatment of bacterial infections

G Li, Z Lai, A Shan - Advanced Science, 2023 - Wiley Online Library
Owing to the increase in multidrug‐resistant bacterial isolates in hospitals globally and the
lack of truly effective antimicrobial agents, antibiotic resistant bacterial infections have …

Design and synthesis of novel antimicrobial agents

Z Breijyeh, R Karaman - Antibiotics, 2023 - mdpi.com
The necessity for the discovery of innovative antimicrobials to treat life-threatening diseases
has increased as multidrug-resistant bacteria has spread. Due to antibiotics' availability over …

Advancements in peptide-based antimicrobials: A possible option for emerging drug-resistant infections

N Yadav, VS Chauhan - Advances in Colloid and Interface Science, 2024 - Elsevier
In recent years, multidrug-resistant pathogenic microorganisms (MDROs) have emerged as
a severe threat to human health, exhibiting robust resistance to traditional antibiotics. This …

Microbiome-derived antimicrobial peptides offer therapeutic solutions for the treatment of Pseudomonas aeruginosa infections

AJ Mulkern, LB Oyama, AR Cookson… - npj Biofilms and …, 2022 - nature.com
Microbiomes are rife for biotechnological exploitation, particularly the rumen microbiome,
due to their complexicity and diversity. In this study, antimicrobial peptides (AMPs) from the …

Plant antimicrobial peptides (PAMPs): features, applications, production, expression, and challenges

OO Bakare, A Gokul, AO Fadaka, R Wu, LA Niekerk… - Molecules, 2022 - mdpi.com
The quest for an extraordinary array of defense strategies is imperative to reduce the
challenges of microbial attacks on plants and animals. Plant antimicrobial peptides (PAMPs) …

Microbial derived antimicrobial peptides as potential therapeutics in atopic dermatitis

AA Joshi, M Vocanson, JF Nicolas, P Wolf… - Frontiers in …, 2023 - frontiersin.org
Atopic dermatitis (AD) is a common chronic inflammatory skin disease that significantly
affects the patient's quality of life. A disrupted skin barrier, type 2 cytokine-dominated …

Perspectives in searching antimicrobial peptides (AMPs) produced by the microbiota

L Gallardo-Becerra, M Cervantes-Echeverría… - Microbial Ecology, 2024 - Springer
Abstract Changes in the structure and function of the microbiota are associated with various
human diseases. These microbial changes can be mediated by antimicrobial peptides …

Recent advances in genome mining and synthetic biology for discovery and biosynthesis of natural products

M Wang, L Chen, Z Zhang, Q Wang - Critical Reviews in …, 2025 - Taylor & Francis
Natural products have long served as critical raw materials in chemical and pharmaceutical
manufacturing, primarily which can provide superior scaffolds or intermediates for drug …

Accessing hidden microbial biosynthetic potential from underexplored sources for novel drug discovery

L Li - Biotechnology Advances, 2023 - Elsevier
Microbial natural products and their structural analogues have widely used as
pharmaceutical agents, especially for infectious diseases and cancer. Despite this success …

Discovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant …

WK Mousa, R Ghemrawi, T Abu-Izneid… - International journal of …, 2023 - mdpi.com
The human body is a superorganism that harbors trillions of microbes, most of which inhabit
the gut. To colonize our bodies, these microbes have evolved strategies to regulate the …