[HTML][HTML] Biological activity and toxicity of the Chinese herb Magnolia officinalis Rehder & E. Wilson (Houpo) and its constituents

M Poivre, P Duez - Journal of Zhejiang University. Science. B, 2017 - ncbi.nlm.nih.gov
Traditional Chinese herbal drugs have been used for thousands of years in Chinese
pharmacopoeia. The bark of Magnolia officinalis Rehder & E. Wilson, known under the …

[HTML][HTML] Function of selected natural antidiabetic compounds with potential against cancer via modulation of the PI3K/AKT/mTOR cascade

ADR Nurcahyanti, A Jap, J Lady, D Prismawan… - Biomedicine & …, 2021 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder with growing global incidence, as 387 million
people were diagnosed in 2014 with an expected projection of 642 million in 2040. Several …

Honokiol and its analogues as anticancer compounds: Current mechanistic insights and structure-activity relationship

P Prasher, R Fatima, M Sharma, B Tynybekov… - Chemico-biological …, 2023 - Elsevier
Lignans are plant-derived polyphenolic compounds with a plethora of biological
applications. Also, regarded as phytoestrogens, the lignans offer a variety of health benefits …

[HTML][HTML] Honokiol suppresses renal cancer cells' metastasis via dual-blocking epithelial-mesenchymal transition and cancer stem cell properties through modulating …

W Li, Q Wang, Q Su, D Ma, C An, L Ma, H Liang - Molecules and cells, 2014 - Elsevier
Renal cell carcinoma (RCC) is associated with a high frequency of metastasis and only few
therapies substantially prolong survival. Honokiol, isolated from Magnolia spp. bark, has …

Neuraminidase 1 regulates proliferation, apoptosis and the expression of Cadherins in mammary carcinoma cells

P Thulasiraman, K Kerr, K McAlister, S Hardisty… - Molecular and Cellular …, 2019 - Springer
Abstract The link between Neuraminidase 1 (Neu1) and cancer development has been
highlighted in numerous studies. In an effort to understand the role of Neu1 in mammary …

[HTML][HTML] Synthesis of obovatol and related neolignan analogues as α-glucosidase and α-amylase inhibitors

C Sciacca, N Cardullo, L Pulvirenti, G Travagliante… - Bioorganic …, 2024 - Elsevier
Diabetes mellitus is a metabolic disease characterized by hyperglycemia, which can be
counteracted by the inhibition of α-glucosidase (α-Glu) and α-amylase (α-Amy), enzymes …

Biotin-modified oligochitosan-F127 micelles for honokiol's encapsulation

L Zhu, Z Song, S Feng, H Xu, S Chen… - Journal of Nanoparticle …, 2021 - Springer
In the study, biotin-modified oligochitosan-F127 conjugate (F127-CS-BIO) was synthesized
as a carrier to prepare honokiol-loaded micelles via dialysis method. The encapsulation …