Genome-wide association studies in ADHD

B Franke, BM Neale, SV Faraone - Human genetics, 2009 - Springer
Attention-deficit/hyperactivity disorder, ADHD, is a common and highly heritable
neuropsychiatric disorder that is seen in children and adults. Although heritability is …

Family-based designs for genome-wide association studies

J Ott, Y Kamatani, M Lathrop - Nature Reviews Genetics, 2011 - nature.com
Association mapping has successfully identified common SNPs associated with many
diseases. However, the inability of this class of variation to account for most of the supposed …

Meta-analysis of 32 genome-wide linkage studies of schizophrenia

MYM Ng, DF Levinson, SV Faraone, BK Suárez… - Molecular …, 2009 - nature.com
A genome scan meta-a nalysis (GSMA) was carried out on 32 independent genome-wide
linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases affected …

[图书][B] Consanguinity in context

AH Bittles - 2012 - books.google.com
An essential guide to this major contemporary issue, Consanguinity in Context is a uniquely
comprehensive account of intra-familial marriage. Detailed information on past and present …

Using multivariate machine learning methods and structural MRI to classify childhood onset schizophrenia and healthy controls

D Greenstein, JD Malley, B Weisinger, L Clasen… - Frontiers in …, 2012 - frontiersin.org
Introduction: Multivariate machine learning methods can be used to classify groups of
schizophrenia patients and controls using structural magnetic resonance imaging (MRI) …

Association of the Type 2 Diabetes Mellitus Susceptibility Gene, TCF7L2, with Schizophrenia in an Arab-Israeli Family Sample

A Alkelai, L Greenbaum, S Lupoli, Y Kohn… - PloS one, 2012 - journals.plos.org
Many reports in different populations have demonstrated linkage of the 10q24–q26 region to
schizophrenia, thus encouraging further analysis of this locus for detection of specific …

A systematic review of genome-wide association studies of antipsychotic response

JD Allen, JR Bishop - Pharmacogenomics, 2019 - Taylor & Francis
Clinical symptom response to antipsychotic medications is highly variable. Genome-wide
association studies (GWAS) provide a 'hypothesis-free'method of interrogating the genome …

A family-based association study of DNA sequence variants in GRM7 with schizophrenia in an Indonesian population

C Ganda, SG Schwab, N Amir, H Heriani… - International Journal …, 2009 - academic.oup.com
We previously reported genome-wide significant linkage to chromosome 3p in a sib-pair
family sample from Indonesia. A promising candidate gene within the linked region is the …

A Novel Microduplication in the Neurodevelopmental Gene SRGAP3 That Segregates with Psychotic Illness in the Family of a COS Proband

NKA Wilson, Y Lee, R Long, K Hermetz… - Case reports in …, 2011 - Wiley Online Library
Schizophrenia is a debilitating mental disorder affecting approximately 1% of the world′ s
population. Childhood onset schizophrenia (COS), defined as onset before age 13, is a rare …

Polymorphisms of XRCC4 are involved in reduced colorectal cancer risk in Chinese schizophrenia patients

Y Wang, L Wang, X Li, B Liu, Q Zhao, P Chen, T Wang… - BMC cancer, 2010 - Springer
Background Genetic factors related to the regulation of apoptosis in schizophrenia patients
may be involved in a reduced vulnerability to cancer. XRCC4 is one of the potential …