The impact of oxidative stress on blood-retinal barrier physiology in age-related macular degeneration

A Tisi, M Feligioni, M Passacantando, M Ciancaglini… - Cells, 2021 - mdpi.com
The blood retinal barrier (BRB) is a fundamental eye component, whose function is to select
the flow of molecules from the blood to the retina and vice-versa, and its integrity allows the …

Retinitis pigmentosa and allied diseases: numerous diseases, genes, and inheritance patterns

C Rivolta, D Sharon, MM DeAngelis… - Human molecular …, 2002 - academic.oup.com
Retinitis pigmentosa (RP) and allied diseases are heterogeneous clinically and genetically.
Here we summarize the retinal cell types involved in these diseases, the large number of …

Age‐related alterations in the dynamic behavior of microglia

MR Damani, L Zhao, AM Fontainhas, J Amaral… - Aging cell, 2011 - Wiley Online Library
Microglia, the primary resident immune cells of the central nervous system (CNS), exhibit
dynamic behavior involving rapid process motility and cellular migration that is thought to …

Retinal electrophysiology in central nervous system disorders. A review of human and mouse studies

PA Constable, JKH Lim, DA Thompson - Frontiers in Neuroscience, 2023 - frontiersin.org
The retina and brain share similar neurochemistry and neurodevelopmental origins, with the
retina, often viewed as a “window to the brain.” With retinal measures of structure and …

Schizophrenia and the retina: towards a 2020 perspective

SM Silverstein, SI Fradkin, DL Demmin - Schizophrenia research, 2020 - Elsevier
Background Differences between people with schizophrenia and psychiatrically healthy
controls have been consistently demonstrated on measures of retinal function such as …

The role of docosahexaenoic acid in retinal function

BG Jeffrey, HS Weisinger, M Neuringer, DC Mitchell - Lipids, 2001 - Wiley Online Library
An important role for docosahexaenoic acid (DHA) within the retina is suggested by its high
levels and active conservation in this tissue. Animals raised on n‐3‐deficient diets have …

Oscillatory potential analysis and ERGs of normal and diabetic rats

HA Hancock, TW Kraft - Investigative ophthalmology & visual …, 2004 - iovs.arvojournals.org
purpose. To identify and characterize the early alterations of the ERG oscillatory potentials
(OPs) under conditions of poor glycemic control associated with diabetes in an animal …

Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

MP Agbaga, MNA Mandal, RE Anderson - Journal of lipid research, 2010 - ASBMB
Compared with other mammalian tissues, retina is highly enriched in PUFA. Long-chain
PUFA (LC-PUFA; C18-C24) are essential FAs that are enriched in the retina and are …

Structural and functional changes in the retina in Parkinson's disease

JN Alves, BU Westner, A Højlund, RS Weil… - Journal of Neurology …, 2023 - jnnp.bmj.com
Parkinson's disease is caused by degeneration of dopaminergic neurons, originating in the
substantia nigra pars compacta and characterised by bradykinesia, rest tremor and rigidity …

[HTML][HTML] Age-related retinal changes in wild-type C57BL/6J mice between 2 and 32 months

S Ferdous, KL Liao, ID Gefke… - … & visual science, 2021 - arvojournals.org
Purpose: The purpose of this study was to extend our understanding of how aging affects
normal retina function and morphology in wild-type C57BL/6J mice, by analyzing …