Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries
characterized by a local accumulation of cholesterol and non-resolving inflammation …

The vascular endothelial growth factor (VEGF), a homodimeric vasoactive glycoprotein, is
the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is …

Aims Whether and how iron affects the progression of atherosclerosis remains highly
debated. Here, we investigate susceptibility to atherosclerosis in a mouse model (ApoE …

Since the late 1990s, there has been a steady decline in cancer-related mortality, in part
related to the introduction of so-called targeted therapies. Intended to interfere with a specific …

In the United States alone, there are currently approximately 14.5 million cancer survivors,
and this number is expected to increase to 20 million by 2020. Cancer therapies can cause …

Hydrolysable tannins are phenolic phytochemicals that show high antioxidant and free-
radical scavenging activities. For this reason their potential effects preventing oxidative …

Background—Pulmonary hypertension (PH) is driven by diverse pathogenic etiologies.
Owing to their pleiotropic actions, microRNA molecules are potential candidates for …

Abdominal obesity is a major risk factor for cardiovascular disease, and recent studies
highlight a key role of adipose tissue dysfunction, inflammation, and aberrant adipokine …

Several epidemiologic observations show that moderate wine drinking reduces
cardiovascular morbidity and mortality. Wine contains several polyphenols, and among …

Shared angiogenic and oxidative mechanisms underlie the pathophysiology of psoriasis
and atherosclerosis. During the pathogenesis of both diseases, stimuli such as injury or …