Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

Images projected onto the retina of an animal eye are rarely still. Instead, they usually
contain motion signals originating either from moving objects or from retinal slip caused by …

Optokinetic nystagmus (OKN) assists stabilization of the retinal image during head rotation.
OKN is driven by ON direction selective retinal ganglion cells (ON DSGCs), which encode …

Antagonistic interactions between center and surround receptive field (RF) components lie
at the heart of the computations performed in the visual system. Circularly symmetric center …

Visual motion on the retina activates a cohort of retinal ganglion cells (RGCs). This
population activity encodes multiple streams of information extracted by parallel retinal …

Retinal bipolar cells are second-order neurons that transmit basic features of the visual
scene to postsynaptic partners. However, their contribution to motion detection has not been …

Retinal ganglion cells (RGCs) were one of the first classes of sensory neurons to be
described in terms of a receptive field (RF). Over the last six decades, our understanding of …

Sensory systems use receptors to extract information from the environment and neural
circuits to perform subsequent computations. These computations may be described as …

Dendrites in many neurons actively compute information. In retinal starburst amacrine cells,
transformations from synaptic input to output occur within individual dendrites and mediate …

A common strategy by which developing neurons locate their synaptic partners is through
projections to circuit-specific neuropil sublayers. Once established, sublayers serve as a …