The nuclear receptors REV-ERB (consisting of REV-ERBα and REV-ERBβ) and retinoic acid
receptor-related orphan receptors (RORs; consisting of RORα, RORβ and RORγ) are …

Mammalian circadian rhythms are controlled by endogenous biological oscillators, including
a master clock located in the hypothalamic suprachiasmatic nuclei (SCN). Since the period …

Natriuretic peptides are a family of three structurally related hormone/paracrine factors. Atrial
natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are secreted from the cardiac …

As a chemical transmitter in the mammalian central nervous system, nitric oxide (NO) is still
thought a bit of an oddity, yet this role extends back to the beginnings of the evolution of the …

To facilitate the study of the CaMKIIα function in vivo, a CaMKIIα-GFP transgenic mouse line
was generated. Here, our goal is to provide the first neuroanatomical characterization of …

Highlights What are the main findings? Hypothesis: Redox, bioenergetic and temperature
regulation is critical in maintaining cellular circadian rhythms; wakefulness is mainly …

Animals synchronize to the environmental day-night cycle by means of an internal circadian
clock in the brain. In mammals, this timekeeping mechanism is housed in the …

Neuroendocrine mechanisms are major determinants of the normal 24-h blood pressure
(BP) pattern. At the central level, integration of the major driving factors of this temporal …

INTRODUCTION Reindeer (Rangifer tarandus) are naturally distributed across the Arctic
and subarctic regions. Consequently, these animals have evolved to face numerous …

Nitric oxide (NO) is a remarkable gaseous molecule with multiple and important roles in
different organisms, including fungi. However, the study of the biology of NO in fungi has …