Fatty-acid-binding proteins: From lipid transporters to disease biomarkers

S Gaffar, AS Aathirah - Biomolecules, 2023 - mdpi.com
Fatty-acid-binding proteins (FABPs) serve a crucial role in the metabolism and transport of
fatty acids and other hydrophobic ligands as an intracellular protein family. They are also …

[HTML][HTML] Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons

Q Guo, I Kawahata, A Cheng, H Wang, W Jia… - Redox Biology, 2023 - Elsevier
We have previously shown that a fatty acid-binding protein7 (FABP7) inhibitor ameliorates
cerebral ischemia-reperfusion injury in mice, suggesting an association between FABPs and …

The role of astrocyte metabolic reprogramming in ischemic stroke

W Chen, T Mao, R Ma, Y Xiong… - International …, 2025 - spandidos-publications.com
Ischemic stroke, a leading cause of disability and mortality worldwide, is characterized by
the sudden loss of blood flow in specific area of the brain. Intravenous thrombolysis with …

Peripheral inflammation-induced changes in songbird brain gene expression: 3'mRNA transcriptomic approach

NK Veetil, HC de Oliveira, M Gomez-Samblas… - Developmental & …, 2024 - Elsevier
Species-specific neural inflammation can be induced by profound immune signalling from
periphery to brain. Recent advances in transcriptomics offer cost-effective approaches to …

α‐Synuclein decoy peptide protects mice against α‐synuclein‐induced memory loss

Q Guo, I Kawahata, W Jia, H Wang… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims We previously found that a decoy peptide derived from the C‐terminal sequence of α‐
Synuclein (αSyn) prevents cytotoxic αSyn aggregation caused by fatty acid‐binding protein …

A data mining approach to identify key radioresponsive genes in mouse model of radiation-induced intestinal injury

S Sharma, A Rehan, A Dutta - Biomarkers, 2024 - Taylor & Francis
Background Radiation-mediated GI injury (RIGI) is observed in humans either due to
accidental or intentional exposures. This can only be managed with supporting care and no …

Analysis of Serum Markers of Perioperative Brain Injury and Inflammation Associated with Endovascular Treatment of Intracranial Aneurysms: A Preliminary Study

M Zimny, P Paździora, D Kocur, B Błaszczyk… - Brain Sciences, 2023 - mdpi.com
Embolization is the preferred method for treating intracranial aneurysms due to its less
invasive nature. However, recent findings suggest that even uncomplicated embolization …

[HTML][HTML] GPR124 induces NLRP3 inflammasome-mediated pyroptosis in endothelial cells during ischemic injury

Y Xu, X Fang, Z Zhao, H Wu, H Fan, Y Zhang… - European Journal of …, 2024 - Elsevier
Objective G protein-coupled receptor 124 (GPR124) regulates central nervous system
angiogenesis and blood-brain barrier (BBB) integrity, and its deficiency aggravates BBB …

H-FABP as a Biomarker in Transient Ischemic Attack

D Guamán-Pilco, E Chocano, E Palà… - Journal of …, 2024 - Springer
The study investigates the utility of heart fatty-acid binding protein (H-FABP) in distinguishing
TIA from mimics. Data from 175 patients from the StrokeChip multicenter study was …

Electronic medical record data analysis and prediction of stroke disease using Explainable Artificial Intelligence (XAI)

Y Pamungkas, AD Wibawa… - Kinetik: Game Technology …, 2022 - kinetik.umm.ac.id
The deficiency of oxygen in the brain will cause the cells to die, and the body parts
controlled by the brain cells will become dysfunctional. Damage or rupture of blood vessels …