Evasion of apoptosis is one of the crucial acquired capabilities used by cancer cells to fend
off anticancer therapies. Inhibitor of apoptosis (IAP) proteins exert a range of biological …

Simple Summary The Inhibitor of Apoptosis (IAP) family of proteins has emerged as a
potential pharmacological target in cancer. Abnormal expression of IAPs can lead to …

Inhibitor of apoptosis (IAP) family comprises a group of endogenous proteins that function as
main regulators of caspase activity and cell death. They are considered the main culprits in …

The inhibitors of apoptosis (IAPs) constitute a family of proteins involved in the regulation of
various cellular processes, including cell death, immune and inflammatory responses, cell …

The heterogeneous group of diseases collectively termed cancer results not just from
aberrant cellular proliferation but also from a lack of accompanying homeostatic cell death …

Inhibitor of Apoptosis (IAP) proteins exert essential functions during tumorigenesis as well as
treatment resistance by simultaneously blocking cell death pathways and promoting cell …

Hepatocellular carcinoma (HCC) is one of the most common malignancies, with a very poor
prognosis. Despite significant improvements in diagnosis and treatment in recent years, the …

Background Leukemia stem cell (LSC)-enriched genes have been shown to be highly
prognostic in acute myeloid leukemia (AML). However, the prognostic value of tumor …

Head and neck squamous cell carcinoma (HNSCC) ranks as the eighth most prevalent
malignancy globally and has the eighth greatest fatality rate when compared to all other …

Resistance to apoptosis is one of the hallmarks of human cancers and contributes to the
insensitivity of many cancers to commonly used treatment approaches. Inhibitor of apoptosis …