Obesity in autoimmune diseases: not a passive bystander

M Versini, PY Jeandel, E Rosenthal, Y Shoenfeld - Autoimmunity reviews, 2014 - Elsevier
In the last decades, autoimmune diseases have experienced a dramatic increase in Western
countries. The involvement of environmental factors is strongly suspected to explain this rise …

Impact of obesity on remission and disease activity in rheumatoid arthritis: a systematic review and meta‐analysis

Y Liu, GS Hazlewood, GG Kaplan… - Arthritis care & …, 2017 - Wiley Online Library
Objective To summarize the relationship between obesity and remission in rheumatoid
arthritis (RA); secondary objectives were to summarize other measures of treatment …

Effect of body mass index on treatment response of biologic/targeted-synthetic DMARDs in patients with rheumatoid arthritis, psoriatic arthritis or axial spondyloarthritis …

CG Gialouri, M Pappa, G Evangelatos… - Autoimmunity …, 2023 - Elsevier
Background Overweight and/or obese patients with inflammatory arthritis (IA) have higher
disease activity and lower chances of achieving and/or maintaining the treatment targets …

Overweight decreases the chance of achieving good response and low disease activity in early rheumatoid arthritis

MEC Sandberg, C Bengtsson, H Källberg… - Annals of the …, 2014 - ard.bmj.com
Aim To investigate whether overweight/obesity at diagnosis affects the chances of decrease
in disease activity and pain in early rheumatoid arthritis (RA). Method We investigated …

Obesity as a risk and severity factor in rheumatic diseases (autoimmune chronic inflammatory diseases)

E Gremese, B Tolusso, MR Gigante… - Frontiers in …, 2014 - frontiersin.org
The growing body of evidence recognizing the adipose tissue (AT) as an active endocrine
organ secreting bioactive mediators involved in metabolic and inflammatory disorders …

Diet as a modulator of intestinal microbiota in rheumatoid arthritis

E Dourado, M Ferro, C Sousa Guerreiro, JE Fonseca - Nutrients, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a chronic immune-driven inflammatory disease characterised by
synovial inflammation, leading to progressive cartilage and bone destruction, impacting …

Mechanisms underlying DMARD inefficacy in difficult-to-treat rheumatoid arthritis: a narrative review with systematic literature search

NMT Roodenrijs, PMJ Welsing, J van Roon… - …, 2022 - academic.oup.com
Management of RA patients has significantly improved over the past decades. However, a
substantial proportion of patients is difficult-to-treat (D2T), remaining symptomatic after …

The obesity epidemic and consequences for rheumatoid arthritis care

MD George, JF Baker - Current rheumatology reports, 2016 - Springer
With the prevalence of obesity increasing dramatically worldwide over the past several
decades, an increasing body of literature has examined the impact of obesity in the context …

Impact of obesity and adiposity on inflammatory markers in patients with rheumatoid arthritis

MD George, JT Giles, PP Katz… - Arthritis care & …, 2017 - Wiley Online Library
Objective The C‐reactive protein (CRP) level and erythrocyte sedimentation rate (ESR) are
important disease activity biomarkers in rheumatoid arthritis (RA). This study aimed to …

Obesity is a strong predictor of worse clinical outcomes and treatment responses in early rheumatoid arthritis: results from the SWEFOT trial

A Levitsky, K Brismar, I Hafström… - RMD open, 2017 - rmdopen.bmj.com
Objectives The aim of this paper was to analyse the impact of obesity, in addition to known
predictors, on disease outcome in early rheumatoid arthritis (RA). Methods Body mass index …