The circadian regulation of food intake

E Challet - Nature Reviews Endocrinology, 2019 - nature.com
Feeding, which is essential for all animals, is regulated by homeostatic mechanisms. In
addition, food consumption is temporally coordinated by the brain over the circadian (~ 24 h) …

Coupled network of the circadian clocks: a driving force of rhythmic physiology

AM Finger, C Dibner, A Kramer - FEBS letters, 2020 - Wiley Online Library
The circadian system is composed of coupled endogenous oscillators that allow living
beings, including humans, to anticipate and adapt to daily changes in their environment. In …

Circadian disruption promotes tumor-immune microenvironment remodeling favoring tumor cell proliferation

I Aiello, MLM Fedele, F Román, L Marpegan… - Science …, 2020 - science.org
Circadian disruption negatively affects physiology, posing a global health threat that
manifests in proliferative, metabolic, and immune diseases, among others. Because outputs …

Poor sleep and shift work associate with increased blood pressure and inflammation in UK Biobank participants

M Kanki, AP Nath, R Xiang, S Yiallourou… - Nature …, 2023 - nature.com
Disrupted circadian rhythms have been linked to an increased risk of hypertension and
cardiovascular disease. However, many studies show inconsistent findings and are not …

Shift work and the risk of cardiometabolic multimorbidity among patients with hypertension: a prospective cohort study of UK biobank

L Yang, Y Luo, L He, J Yin, T Li, S Liu, D Li… - Journal of the …, 2022 - Am Heart Assoc
Background Although the association between shift work and individual cardiometabolic
diseases has been well studied, its role in the progression to cardiometabolic multimorbidity …

Circadian disruption and consequences on innate immunity and inflammatory response

V Jerigova, M Zeman, M Okuliarova - International Journal of Molecular …, 2022 - mdpi.com
Circadian rhythms control almost all aspects of physiology and behavior, allowing temporal
synchrony of these processes between each other, as well as with the external environment …

Innate rhythms: clocks at the center of monocyte and macrophage function

GA Timmons, JR O'Siorain, OD Kennedy… - Frontiers in …, 2020 - frontiersin.org
The circadian cycle allows organisms to track external time of day and predict/respond to
changes in the external environment. In higher order organisms, circadian rhythmicity is a …

Circadian rhythms and pancreas physiology: A review

K Chan, FS Wong, JA Pearson - Frontiers in Endocrinology, 2022 - frontiersin.org
Type 2 diabetes mellitus, obesity and metabolic syndrome are becoming more prevalent
worldwide and will present an increasingly challenging burden on healthcare systems …

REV-ERB nuclear receptors in the suprachiasmatic nucleus control circadian period and restrict diet-induced obesity

M Adlanmerini, BM Krusen, HCB Nguyen, CW Teng… - Science …, 2021 - science.org
Circadian disruption, as occurs in shift work, is associated with metabolic diseases often
attributed to a discordance between internal clocks and environmental timekeepers. REV …

Disruption of circadian rhythm by alternating light‐dark cycles aggravates atherosclerosis development in APOE* 3‐Leiden. CETP mice

M Schilperoort, R van den Berg… - Journal of pineal …, 2020 - Wiley Online Library
Disruption of circadian rhythm by means of shift work has been associated with
cardiovascular disease in humans. However, causality and underlying mechanisms have …