[HTML][HTML] The role of PPM1D in cancer and advances in studies of its inhibitors

W Deng, J Li, K Dorrah, D Jimenez-Tapia… - Biomedicine & …, 2020 - Elsevier
A greater understanding of factors causing cancer initiation, progression and evolution is of
paramount importance. Among them, the serine/threonine phosphatase PPM1D, also …

IL‐17 induces non‐small cell lung cancer metastasis via GCN5‐dependent SOX4 acetylation enhancing MMP9 gene transcription and expression

W Ge, Y Gong, Y Li, N Wu, Y Ruan, T Xu… - Molecular …, 2023 - Wiley Online Library
Abstract Interleukin‐17 (IL‐17), a potent proinflammatory cytokine, can trigger the metastasis
of non‐small cell lung cancer (NSCLC). However, the underlying mechanism involved in IL …

Nanotechnology based repositioning of an anti-viral drug for non-small cell lung cancer (NSCLC)

V Parvathaneni, M Goyal, NS Kulkarni… - Pharmaceutical …, 2020 - Springer
Abstract Purpose Nelfinavir (NFV), a FDA approved antiretroviral drug, has been reported to
exhibit cancer cells growth inhibition and increased apoptosis. However, it requires a higher …

Circ_SETD3 regulates gefitinib sensitivity and tumor progression by miR-873-5p-dependent regulation of APPBP2 in non-small cell lung cancer

J Sheng, L Liu, T Dong, X Wu - Journal of Chemotherapy, 2022 - Taylor & Francis
Previous data have shown the prominent clinical efficacy of gefitinib in non-small cell lung
cancer (NSCLC) patients. However, its therapeutic efficacy is limited because of the …

circBIRC6 contributes to the development of non-small cell lung cancer via regulating microRNA-217/amyloid beta precursor protein binding protein 2 axis

D Ni, J Teng, Y Cheng, Z Zhu, B Zhuang… - Chinese medical …, 2022 - mednexus.org
Background: Circular RNAs (circRNAs) are considered to be important regulators in cancer
biology. In this study, we focused on the effect of circRNA baculoviral inhibitor of apoptosis …

Analysis of ceRNA network of differentially expressed genes in FaDu cell line and a cisplatin-resistant line derived from it

G Zhang, G Tan, T Li, J Ai, Y Song, Z Zhou, J Xiao, W Li - PeerJ, 2021 - peerj.com
Background Hypopharyngeal cancer accounts for 2% in head and neck cancers and has a
poor prognosis. Cisplatin is a widely used chemotherapeutic drug in kinds of carcinomas …