Glycemic variability: adverse clinical outcomes and how to improve it?

Z Zhou, B Sun, S Huang, C Zhu, M Bian - Cardiovascular diabetology, 2020 - Springer
Glycemic variability (GV), defined as an integral component of glucose homoeostasis, is
emerging as an important metric to consider when assessing glycemic control in clinical …

Comprehensive elaboration of glycemic variability in diabetic macrovascular and microvascular complications

B Sun, Z Luo, J Zhou - Cardiovascular Diabetology, 2021 - Springer
Diabetes mellitus is the major risk factor for the development of macrovascular and
microvascular complications. It is increasingly recognized that glycemic variability (GV) …

[HTML][HTML] Glycemic variability: how to measure and its clinical implication for type 2 diabetes

GE Umpierrez, BP Kovatchev - The American journal of the medical …, 2018 - Elsevier
Glycated hemoglobin A 1c (A1C) levels have traditionally been the gold standard for
assessing glycemic control and treatment efficacy in patients with type 2 diabetes. However …

Anti-inflammatory properties of antidiabetic drugs: a “promised land” in the COVID-19 era?

N Katsiki, E Ferrannini - Journal of Diabetes and its Complications, 2020 - Elsevier
Inflammation is implicated in the development and severity of the coronavirus disease 2019
(COVID-19), as well as in the pathophysiology of diabetes. Diabetes, especially when …

Efficacy and safety of pioglitazone monotherapy in type 2 diabetes mellitus: a systematic review and meta-analysis of randomised controlled trials

F Alam, MA Islam, M Mohamed, I Ahmad, MA Kamal… - Scientific reports, 2019 - nature.com
Pioglitazone, the only thiazolidinedione drug in clinical practice is under scrutiny due to
reported adverse effects, it's unique insulin sensitising action provides rationale to remain as …

CGMS and glycemic variability, relevance in clinical research to evaluate interventions in T2D, a literature review

AE Breyton, S Lambert-Porcheron, M Laville… - Frontiers in …, 2021 - frontiersin.org
Glycemic variability (GV) appears today as an integral component of glucose homeostasis
for the management of type 2 diabetes (T2D). This review aims at investigating the use and …

Effect of DPP-IV inhibitors on glycemic variability in patients with T2DM: a systematic review and meta-analysis

S Lee, H Lee, Y Kim, EY Kim - Scientific reports, 2019 - nature.com
Glycemic variability (GV) has been an emerging target for preventing complications related
to type 2 diabetes. For reducing GV, DPP-IV inhibitors have shown effectiveness compared …

Impact of long-term glucose variability on coronary atherosclerosis progression in patients with type 2 diabetes: a 2.3 year follow-up study

S Li, X Tang, Y Luo, B Wu, Z Huang, Z Li… - Cardiovascular …, 2020 - Springer
Background Glycemic variability (GV) confers a risk of cardiovascular events. In this study,
we aimed to investigate whether long-term GV has an impact on coronary atherosclerosis …

Visit-to-visit fasting plasma glucose variability is an important risk factor for long-term changes in left cardiac structure and function in patients with type 2 diabetes

X Tang, J Zhong, H Zhang, Y Luo, X Liu, L Peng… - Cardiovascular …, 2019 - Springer
Background To investigate the effect of visit-to-visit fasting plasma glucose (FPG) variability
on the left cardiac structure and function in patients with type 2 diabetes mellitus (T2DM) …

[HTML][HTML] Effect of dapagliflozin as an add-on therapy to insulin on the glycemic variability in subjects with type 2 diabetes mellitus (DIVE): a multicenter, placebo …

SH Lee, KW Min, BW Lee, IK Jeong… - Diabetes & …, 2021 - synapse.koreamed.org
Background Glycemic variability is associated with the development of diabetic
complications and hypoglycemia. However, the effect of sodium-glucose transporter 2 …