Immune responses to human fungal pathogens and therapeutic prospects

MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …

The rapid emergence of antifungal-resistant human-pathogenic fungi

SR Lockhart, A Chowdhary, JAW Gold - Nature Reviews Microbiology, 2023 - nature.com
During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …

Worldwide emergence of fluconazole-resistant Candida parapsilosis: current framework and future research roadmap

F Daneshnia, JN de Almeida Júnior, M Ilkit… - The Lancet …, 2023 - thelancet.com
Candida parapsilosis is one of the most commen causes of life-threatening candidaemia,
particularly in premature neonates, individuals with cancer of the haematopoietic system …

Fungal endocarditis: pathophysiology, epidemiology, clinical presentation, diagnosis, and management

GR Thompson III, JD Jenks, JW Baddley… - Clinical microbiology …, 2023 - Am Soc Microbiol
Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …

Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19

T Kusakabe, WY Lin, JG Cheong, G Singh… - Nature …, 2023 - nature.com
Gastrointestinal fungal dysbiosis is a hallmark of several diseases marked by systemic
immune activation. Whether persistent pathobiont colonization during immune alterations …

Cryptococcus neoformans, a global threat to human health

Y Zhao, L Ye, F Zhao, L Zhang, Z Lu, T Chu… - Infectious Diseases of …, 2023 - mednexus.org
Background Emerging fungal pathogens pose important threats to global public health. The
World Health Organization has responded to the rising threat of traditionally neglected …

Invasive candidiasis

C Lass-Flörl, SS Kanj, NP Govender… - Nature Reviews …, 2024 - nature.com
Invasive candidiasis is an important fungal disease caused by Candida albicans and,
increasingly, non-albicans Candida pathogens. Invasive Candida infections originate most …

An overlooked and underrated endemic mycosis—Talaromycosis and the pathogenic fungus Talaromyces marneffei

F Wang, RH Han, S Chen - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Talaromycosis is an invasive mycosis endemic in tropical and subtropical Asia and is
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …

[HTML][HTML] Fungal infections: immune defense, immunotherapies and vaccines

JT Loh, KP Lam - Advanced Drug Delivery Reviews, 2023 - Elsevier
Invasive fungal infection is an under recognized and emerging global health threat.
Recently, the World Health Organization (WHO) released the first ever list of health …

[HTML][HTML] Multicenter case–control study of COVID-19–associated mucormycosis outbreak, India

V Muthu, R Agarwal, SM Rudramurthy… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
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Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is jointly accredited with …