Hypochlorous acid induced structural and conformational modifications in human DNA: A multi-spectroscopic study

IQ Tantry, S Waris, S Habib, RH Khan… - International journal of …, 2018 - Elsevier
Hypochlorous acid (HOCl) is generated by activated phagocytes at the site of inflammation.
Exposure of DNA to HOCl results in base and nucleotide modifications causing DNA …

Neo-epitopes on crotonaldehyde modified DNA preferably recognize circulating autoantibodies in cancer patients

B ul Islam, P Ahmad, G Rabbani, K Dixit, Moinuddin… - Tumor Biology, 2016 - Springer
DNA damage is one of the leading causes of various pathological conditions including
carcinogenesis. Crotonaldehyde is a 4-carbon unsaturated bifunctional aldehyde which is …

Preferential recognition of specific DNA motifs by anti‐double‐stranded DNA autoantibodies

M Herrmann, TH Winkler, H Fehr… - European journal of …, 1995 - Wiley Online Library
Although antibodies (Ab) specific for double‐stranded (ds) DNA are thought to be involved
in the etiopathogenesis of systemic lupus erythematosus (SLE), the fine structure of their …

Genotoxicity and immunogenicity of crotonaldehyde modified human DNA

BU Islam, R Mahmood, A Ali - International journal of biological …, 2014 - Elsevier
DNA damage plays an important role in mutagenesis, carcinogenesis, aging and several
other pathophysiological conditions. Crotonaldehyde is a four carbon unsaturated …

[图书][B] Immunonutrition: Interactions of diet, genetics, and inflammation

BB Aggarwal, D Heber - 2014 - books.google.com
The interaction of immune function and nutrition underlies the low-grade chronic
inflammation involved in the etiology of many common obesity-associated and age-related …

Native DNA fragments photocrosslinked to psoralen binds to anti-B and anti-Z DNA antibodies

S Arjumand, Z Arif, A Ali, R Ali - Immunology letters, 1995 - Elsevier
Calf thymus DNA fragments of varying size (100–600 bp) were covalently linked to psoralen
in the presence of 365 nm UV light. The crosslinked species were separated from the …

Binding characteristics of sle anti‐DNA autoantibodies to modified DNA analogue

S Arjumand, A Ali - IUBMB Life, 1997 - Wiley Online Library
Native calf thymus DNA was modified with furoconmarins and reactive oxygen species
(ROS). The modifications were probed by UV & Fluorescence spectroscopy, thermal …

Possible augmentation of photosensitivity by dietary furanocoumarins in patients with systemic lupus erythematosus

R Rastmanesh, AN Baer - Lupus, 2011 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is an autoimmune disease with characteristic
involvement of multiple organ systems, resulting in photosensitive skin eruptions, arthritis …

SLE autoantibodies binding to native calf thymus DNA brominated in high salt

Moinuddin, S Arjumand, A Ali - Lupus, 1998 - journals.sagepub.com
Native calf thymus DNA was brominated in high salt to achieve B→ Z conformational
transition. Ultraviolet and circular dichroism spectroscopic studies point towards the …

[PDF][PDF] jUlaiter of^^ iloiopfip

DK GARG - 1995 - core.ac.uk
jUlaiter of ^^iloiopfip Page 1 IMMUNOLOGICAL STUDIES ON ANTIBODIES AGAINST
INTRACELLULAR AND SECRETED MYCOBACTERIAL PROTEIN ANTIGEN IN …