Simple Summary The canonical WNT/β-catenin pathway is upregulated in cancers and
plays a major role in proliferation, invasion, apoptosis and angiogenesis. Recent studies …

The canonical Wnt/β-catenin pathway is up-regulated in gliomas and involved in
proliferation, invasion, apoptosis, vasculogenesis and angiogenesis. Nuclear β-catenin …

Oral cancer is one of the most frequent malignant diseases worldwide, and areca nut is a
primary carcinogen causing this cancer in Southeast Asia. It has been widely reported that …

Oral cancers (OC) are among the most frequent malignancies encountered in Southeast
Asia, primarily due to the prevalent habit of betel quid (BQ) and smokeless tobacco use in …

Purpose: Increased tumor metabolism and hypoxia are related to poor prognosis in solid
tumors, including non–small cell lung cancer (NSCLC). PET imaging is a noninvasive …

Prior targeted treatment for glioblastoma multiforme (GBM) with anti-angiogenic agents,
such as bevacizumab, has been met with limited success potentially owing to GBM tumor's …

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized
by excessive deposition of fibrotic connective tissue in the lungs. Emerging evidence …

Background Glucose transporter 1 (GLUT1) is encoded by the solute carrier family 2A1
(SLC2A1) gene and is one of the glucose transporters with the greatest affinity for glucose …

TGF-β plays a central role in the pathogenesis of fibroproliferative disorders. Defining the
exact underlying molecular basis is therefore critical for the development of viable …

Laryngeal squamous cell carcinoma (LSCC) is the most common form of laryngeal
carcinoma with poor prognosis. Exploring novel factors involved in the progression of LSCC …