That the renin–angiotensin system (RAS) is involved in regulation of blood pressure,
vasoconstriction, sodium intake and potassium excretion is well established. Studies in the …

The renin-angiotensin system (RAS) is a coordinated hormonal cascade in the control of
cardiovascular, renal, and adrenal function that governs body fluid and electrolyte balance …

The kidney plays a fundamental role in maintaining body salt and fluid balance and blood
pressure homeostasis through the actions of its proximal and distal tubular segments of …

In diabetes mellitus (DM), the circulating renin–angiotensin system (RAS) is suppressed, but
the renal tissue RAS is activated. Hyperglycemia increases tissue angiotensin II (Ang II) …

Intrarenal angiotensin II (Ang II) is regulated by several complex processes involving
formation from both systemically delivered and intrarenally formed substrate, as well as …

The complexity of the intrarenal renin-angiotensin (Ang) system (RAS) continues to reveal
itself as evidence accumulates demonstrating its robust independent regulation in the …

Activation of the intrarenal renin-angiotensin system (RAS) can elicit hypertension
independently from the systemic RAS. However, the precise mechanisms by which …

Combination therapy with ACE inhibitors and angiotensin II receptor blockers to halt
progression of chronic renal disease: Pathophysiology and indications. It is no a secret that …

Renin–angiotensin–aldosterone system (RAAS) plays important roles in regulating renal
hemodynamics and functions, as well as in the pathophysiology of hypertension and renal …

Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production.
Background In rats maintained on a high salt diet (H/S) to suppress basal renal …