The sustainable production of chemicals from renewable, nonedible biomass has emerged
as an essential alternative to address pressing environmental issues arising from our heavy …

The nonconventional, oleaginous yeast, Yarrowia lipolytica is rapidly emerging as a
valuable host for the production of a variety of both lipid and nonlipid chemical products …

Amid growing concerns over the human health and environmental impacts of plastic waste,
the most promising solution would be to build a circular plastics economy where …

Succinic acid (SA) is an important C4-dicarboxylic acid. Microbial production of SA at low pH
results in low purification costs and hence good overall process economics. However, redox …

Polyketides are a diverse class of molecules sought after for their valuable properties,
including as potential pharmaceuticals. Previously, we demonstrated that the oleaginous …

Plants possess myriads of secondary metabolites with a broad spectrum of health-promoting
benefits. To date, plant extraction is still the primary route to produce high-value natural …

The non-conventional oleaginous yeast Yarrowia lipolytica shows great industrial promise. It
naturally produces certain compounds of interest but can also artificially generate non-native …

Background Yarrowia lipolytica, a non-traditional oil yeast, has been widely used as a
platform for lipid production. However, the production of other chemicals such as terpenoids …

Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …

Engineering microbial cells to efficiently synthesize high-value-added natural products has
received increasing attention in recent years. In this review, we describe the pipeline to build …