Aging is a natural but relentless process of physiological decline, leading to physical frailty,
reduced ability to respond to physical stresses (resilience) and, ultimately, organismal death …

Cellular senescence, a cell state characterized by a generally irreversible cell cycle arrest, is
implicated in various physiological processes and a wide range of age-related pathologies …

Mitochondrial and lysosomal functions are intimately linked and are critical for cellular
homeostasis, as evidenced by the fact that cellular senescence, aging, and multiple …

Cellular senescence plays an important role in different biological and pathological
conditions. Senescent cells communicate with their microenvironment through a plethora of …

Skin aging is a complex process influenced by intrinsic factors and environmental stressors,
including ultraviolet (UV) radiation and air pollution, among others. In this study, we …

The contribution of cellular senescence to a diverse range of biological processes, including
normal physiology, ageing, and pathology were long overlooked but have now taken centre …

Aging of human skin is a complex process leading to a decline in homeostasis and
regenerative potential of this tissue. Mitochondria are important cell organelles that have a …

The complex physiology of eukaryotic cells requires that a variety of subcellular organelles
perform unique tasks, even though they form highly dynamic communication networks. In the …

Organelles are tiny structures with specific functions in eukaryotic cells. Since they are
covered with membranes, different organelles can perform biological processes that are …

Molecular mechanisms of aging processes at the level of organisms and cells are in the
focus of a large number of research laboratories. This research culminated in recent …