Towards the optical cochlear implant: optogenetic approaches for hearing restoration

A Dieter, D Keppeler, T Moser - EMBO molecular medicine, 2020 - embopress.org
Cochlear implants (CI s) are considered the most successful neuroprosthesis as they enable
speech comprehension in the majority of half a million CI users suffering from sensorineural …

Outlook and future of inner ear therapy

J Devare, S Gubbels, Y Raphael - Hearing research, 2018 - Elsevier
Drug delivery to the inner ear is an ideal method to treat a wide variety of otologic conditions.
A broad range of potential applications is just beginning to be explored. New approaches …

An approach for individualized cochlear frequency mapping determined from 3D synchrotron radiation phase-contrast imaging

L Helpard, H Li, SA Rohani, N Zhu… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
Objective: Cochlear implants are traditionally programmed to stimulate according to a
generalized frequency map, where individual anatomic variability is not considered when …

On the fabrication and characterization of polymer-based waveguide probes for use in future optical cochlear implants

C Helke, M Reinhardt, M Arnold, F Schwenzer… - Materials, 2022 - mdpi.com
Improved hearing restoration by cochlear implants (CI) is expected by optical cochlear
implants (oCI) exciting optogenetically modified spiral ganglion neurons (SGNs) via an …

Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users

V Hunniford, R Kühler, B Wolf, D Keppeler… - Frontiers in …, 2023 - frontiersin.org
Background The electrical cochlear implant (eCI) partially restores hearing in individuals
affected by profound hearing impairment (HI) or deafness. However, the limited resolution of …

Musical emotion categorization with vocoders of varying temporal and spectral content

EE Harding, E Gaudrain, IJ Hrycyk… - Trends in …, 2023 - journals.sagepub.com
While previous research investigating music emotion perception of cochlear implant (CI)
users observed that temporal cues informing tempo largely convey emotional arousal …

Functional near‐infrared spectroscopy as a tool for assessing speech and spoken language processing in pediatric and adult cochlear implant users

H Bortfeld - Developmental psychobiology, 2019 - Wiley Online Library
Much of what is known about the course of auditory learning in following cochlear
implantation is based on behavioral indicators that users are able to perceive sound. Both …

Conversations in cochlear implantation: the inner ear therapy of today

G Rauterkus, AK Maxwell, JB Kahane, JJ Lentz… - Biomolecules, 2022 - mdpi.com
As biomolecular approaches for hearing restoration in profound sensorineural hearing loss
evolve, they will be applied in conjunction with or instead of cochlear implants. An …

Parameter-specific morphing reveals contributions of timbre and fundamental frequency cues to the perception of voice gender and age in cochlear implant users

VG Skuk, L Kirchen, T Oberhoffner… - Journal of Speech …, 2020 - ASHA
Purpose Using naturalistic synthesized speech, we determined the relative importance of
acoustic cues in voice gender and age perception in cochlear implant (CI) users. Method We …

Rhythm processing in cochlear implant− mediated music perception

NT Jiam, CJ Limb - Annals of the New York Academy of …, 2019 - Wiley Online Library
Cochlear implants (CIs) are biomedical devices that provide sound to people with severe‐to‐
profound hearing loss by direct electrical stimulation of auditory neurons in the cochlea …