Melatonin ameliorates TNBS-induced colitis in rats through the melatonin receptors: involvement of TLR4/MyD88/NF-κB signalling pathway

M Chamanara, A Rashidian, SE Mehr… - …, 2019 - Springer
Aim The aim of the present study is to investigate the anti-inflammatory effect of melatonin in
trinitrobenzene sulfonic acid (TNBS)-induced rat colitis through the inhibition of Toll-like …

Physiological network approach to prognosis in cirrhosis: A shifting paradigm

T Oyelade, KP Moore, AR Mani - Physiological Reports, 2024 - Wiley Online Library
Decompensated liver disease is complicated by multi-organ failure and poor prognosis. The
prognosis of patients with liver failure often dictates clinical management. Current prognostic …

Abnormalities in the 24‐hour rhythm of skin temperature in cirrhosis: Sleep‐wake and general clinical implications

M Garrido, D Saccardo, M De Rui, E Vettore… - Liver …, 2017 - Wiley Online Library
Abstract Background & Aims Sleep preparation/onset are associated with peripheral
vasodilatation and a decrease in body temperature. The hyperdynamic syndrome exhibited …

Nitrergic and opioidergic systems affect radiographic density and histomorphometric indices in bile-duct-ligated cirrhotic rats

AH Doustimotlagh, AR Dehpour, S Etemad Moghadam… - 2017 - digitum.um.es
Metabolic bone disease is a major issue in chronic liver disease. Increased production of
nitric oxide (NO) and elevation of endogenous opioids have been suggested to occur during …

Acute-on-chronic liver disease enhances phenylephrine-induced endothelial nitric oxide release in rat mesenteric resistance arteries through enhanced PKA, PI3K …

L Caracuel, E Sastre, P Llévenes, I Prieto, T Funes… - Scientific reports, 2019 - nature.com
Acute-on-chronic liver disease is a clinical syndrome characterized by decompensated liver
fibrosis, portal hypertension and splanchnic hyperdynamic circulation. We aimed to …

Evidence for the involvement of nitric oxide in cholestasis-induced itch associated response in mice

S Ostadhadi, A Foroutan, M Momeny… - Biomedicine & …, 2016 - Elsevier
Cholestasis is a major systemic disorder associated with distressing pruritus (itch). Nitric
oxide (NO) is a neurotransmitter, assumed to be involved in pruritus. Based on over …

早期肠内免疫微生态营养对原发性肝癌患者术后临床疗效的影响

雍伟 - 实用肝脏病杂志, 2018 - manu43.magtech.com.cn
目的观察原发性肝癌患者行肝癌切除术后早期给予肠内免疫微生态营养支持的临床疗效.
方法120 例行原发性肝癌切除术患者被随机分为观察组60 例和对照组60 例 …

Licofelone, a dual cyclooxygenase/5-lipoxygenase inhibitor, reverses endotoxin-induced impaired atrial chronotropic responsiveness to cholinergic stimulation in rats

V Nikoui, S Mehrzadi, MI Khan, W Aman… - European Journal of …, 2020 - Elsevier
Evidence show that endotoxemia is linked with tachycardia. The exact mechanism of
tachycardia is not well-understood, but it seems that impaired cardiac chronotropic …

[PDF][PDF] Laura Caracuel1, 2, Esther Sastre1, 2, Pablo Llévenes1, Isabel Prieto2, 3, Tania Funes2, 3

MÁ Aller, J Arias, G Balfagón, J Blanco-Rivero - academia.edu
Materials and Methods Animals. Male Wistar rats were obtained and housed in the Animal
Facility of the Universidad Autónoma de Madrid (Registration number EX-021U). The …

تاثیر مشتقات دی هیدروپیریدینی بر ضربان و قدرت انقباضی دهلیز مجزای خوکچه هندی

بختیاریان اعظم, هاشم پور سپیده, عریان شهربانو… - 2018‎ - sid.ir
زمینه و هدف: داروهای مسدد کانال کلسیم مانند نیفدیپین کاربرد فراوانی در درمان بیماری های مختلف
قلبی-عروقی از قبیل آنژین, آریتمی و افزایش فشار خون دارند؛ بنابراین بررسی اثرات قلبی …