Role of endocrine-disrupting chemicals in the pathogenesis of non-alcoholic fatty liver disease: a comprehensive review

R Cano, JL Pérez, LA Dávila, Á Ortega… - International Journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disorder,
affecting around 25% of the population worldwide. It is a complex disease spectrum, closely …

[HTML][HTML] Effects of environmental contaminants in water resources on nonalcoholic fatty liver disease

S Zheng, Y Yang, C Wen, W Liu, L Cao, X Feng… - Environment …, 2021 - Elsevier
The global prevalence of nonalcoholic fatty liver disease (NAFLD) has been increasing
rapidly in recent years, which is now estimated to be over 25%. NAFLD is one of the most …

Metabolomics as a valid analytical technique in environmental exposure research: application and progress

S Wei, Y Wei, Y Gong, Y Chen, J Cui, L Li, H Yan, Y Yu… - Metabolomics, 2022 - Springer
Background In recent years, studies have shown that exposure to environmental pollutants
(eg, radiation, heavy metal substances, air pollutants, organic pollutants) is a leading cause …

Single-cell transcriptomics shows dose-dependent disruption of hepatic zonation by TCDD in mice

R Nault, S Saha, S Bhattacharya, S Sinha… - Toxicological …, 2023 - academic.oup.com
Abstract 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) dose-dependently induces the
development of hepatic fat accumulation and inflammation with fibrosis in mice initially in the …

[HTML][HTML] Low dose exposure to dioxins alters hepatic energy metabolism and steatotic liver disease development in a sex-specific manner

OE Bolatimi, Y Hua, FA Ekuban, TC Gripshover… - Environment …, 2024 - Elsevier
Abstract “Dioxins” are persistent organic pollutants (POPs) that are continuously present in
the environment at appreciable levels and have been associated with increased risk of …

Platelet-activating factor promotes the development of non-alcoholic fatty liver disease

H Yin, A Shi, J Wu - … , metabolic syndrome and obesity: targets and …, 2022 - Taylor & Francis
Non-alcoholic fatty liver disease (NAFLD) is a multifaceted clinicopathological syndrome
characterised by excessive hepatic lipid accumulation that causes steatosis, excluding …

The aryl hydrocarbon receptor regulates lipid mediator production in alveolar macrophages

AM Maier, K Huth, F Alessandrini, F Henkel… - Frontiers in …, 2023 - frontiersin.org
Allergic inflammation of the airways such as allergic asthma is a major health problem with
growing incidence world-wide. One cardinal feature in severe type 2-dominated airway …

Dihydroartemisinin modulated arachidonic acid metabolism and mitigated liver inflammation by inhibiting the activation of 5-LOX and COX-2

Y Xue, J Lu, Y Liu, Y Gao, Y Gong, Y Yang, Y Xiong… - Heliyon, 2024 - cell.com
Background Dihydroartemisinin (DHA), a derivative of Artemisia annua, has been shown to
possess anti-inflammatory properties. Besides, Yes-associated protein 1 (YAP1) plays a …

Multi-omics responses in tree swallow (Tachycineta bicolor) nestlings from the Maumee Area of Concern, Maumee River, Ohio

CY Tseng, CM Custer, TW Custer, PM Dummer… - Science of the Total …, 2023 - Elsevier
A multi-omics approach was utilized to identify altered biological responses and functions,
and to prioritize contaminants to assess the risks of chemical mixtures in the Maumee Area …

内分泌干扰物对机体脂质代谢的影响及其机制研究进展.

李欣慧, 赵飞, 徐倩茹, 施雪卿… - Asian Journals of …, 2021 - search.ebscohost.com
近年来许多动物实验研究表明, 内分泌干扰物(endocrine disrupting chemicals, EDCs)
暴露除了会损伤生殖, 免疫和神经系统等, 还能够干扰脂质代谢, 增加肥胖 …