Vaccines are critical tools for maintaining global health. Traditional vaccine technologies
have been used across a wide range of bacterial and viral pathogens, yet there are a …

The emerging anti-tumor immunotherapy has made significant progress in clinical
application. However, single immunotherapy is not effective for all anti-tumor treatments …

Subunit vaccines are more advantageous than live attenuated vaccines in terms of safety
and scale-up manufacture. However, this often comes as a trade-off to their efficacy. Over …

The immune system is one of the most important, complex biological networks regulating
and protecting human health. Its precise modulation can prevent deadly infections and fight …

Nanomaterials (NMs) have revolutionized multiple aspects of medicine by enabling novel
sensing, diagnostic, and therapeutic approaches. Advancements in processing and …

Nanosized artificial antigen-presenting cells (aAPCs), synthetic immune cell mimics that aim
to activate T cells ex or in vivo, offer an effective alternative to cellular immunotherapies …

Abstract Design of micro-or nanocarriers for drug delivery has primarily been focused on
properties such as hydrophobicity, biodegradability, size, shape, surface charge, and …

Insufficient tumor accumulation and distribution of immunogenic cell death (ICD) inducer as
well as low antitumor immunity severely restrict the therapeutic efficacy of tumor …

The targeting of natural tolerogenic liver sinusoidal endothelial cells (LSEC) by
nanoparticles (NPs), decorated with a stabilin receptor ligand, is capable of generating …

Numerous factors need to be considered to develop a nanodrug delivery system that is
biocompatible, non-toxic, easy to synthesize, cost-effective, and feasible for scale up over …