[HTML][HTML] Cartilage homeostasis and osteoarthritis

Y Fujii, L Liu, L Yagasaki, M Inotsume, T Chiba… - International Journal of …, 2022 - mdpi.com
Healthy limb joints are important for maintaining health and attaining longevity.
Endochondral ossification (the replacement of cartilage with bone, occurring during skeletal …

Non-coding RNAs in development and disease: background, mechanisms, and therapeutic approaches

J Beermann, MT Piccoli, J Viereck… - Physiological …, 2016 - journals.physiology.org
Advances in RNA-sequencing techniques have led to the discovery of thousands of non-
coding transcripts with unknown function. There are several types of non-coding linear …

[HTML][HTML] The host shapes the gut microbiota via fecal microRNA

S Liu, AP Da Cunha, RM Rezende, R Cialic, Z Wei… - Cell host & …, 2016 - cell.com
The host gut microbiota varies across species and individuals but is relatively stable over
time within an individual. How the host selectively shapes the microbiota is largely unclear …

MicroRNAs: history, biogenesis, and their evolving role in animal development and disease

M Bhaskaran, M Mohan - Veterinary pathology, 2014 - journals.sagepub.com
The discovery of microRNAs (miRNAs) in 1993 followed by developments and discoveries
in small RNA biology have redefined the biological landscape by significantly altering the …

MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome …

H Xin, Y Li, Z Liu, X Wang, X Shang, Y Cui… - Stem …, 2013 - academic.oup.com
To test, in vivo, the hypothesis that exosomes from multipotent mesenchymal stromal cells
(MSCs) mediate microRNA 133b (miR-133b) transfer which promotes neurological recovery …

MicroRNA signatures in human cancers

GA Calin, CM Croce - Nature reviews cancer, 2006 - nature.com
MicroRNA (miRNA) alterations are involved in the initiation and progression of human
cancer. The causes of the widespread differential expression of miRNA genes in malignant …

Oncomirs—microRNAs with a role in cancer

A Esquela-Kerscher, FJ Slack - Nature reviews cancer, 2006 - nature.com
MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

S Cheloufi, CO Dos Santos, MMW Chong, GJ Hannon - Nature, 2010 - nature.com
The nucleolytic activity of animal Argonaute proteins is deeply conserved, despite its having
no obvious role in microRNA-directed gene regulation. In mice, Ago2 (also known as Eif2c2) …

Regulation of microRNA function in somatic stem cell proliferation and differentiation

A Shenoy, RH Blelloch - Nature reviews Molecular cell biology, 2014 - nature.com
Abstract microRNAs (miRNAs) are important modulators of development. Owing to their
ability to simultaneously silence hundreds of target genes, they have key roles in large-scale …

The function of microRNAs in cartilage and osteoarthritis

T Swingler, L Niu, P Smith, P Paddy… - Clinical and …, 2019 - ueaeprints.uea.ac.uk
MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression
and have been shown to have key roles in both chondrocyte development and cartilage …